Introduction
Definition of nicotine withdrawal
In those who have developed a nicotine dependence, nicotine withdrawal is the collection of symptoms experienced following either a decrease or cessation of nicotine intake.1
Link between anxiety and nicotine withdrawal
There is a notable link between anxiety and nicotine withdrawal. Although many people smoke to help with stress, studies show that over time, smoking may verily aggravate stress. Nicotine offers brief relief from tension brought on by withdrawal, so establishing a cycle whereby the smoker feels better after smoking, but this relief is fleeting. When nicotine levels drop between each cigarette consumed, anxiety and other withdrawal symptoms reappear and drive the next cigarette. Stress and anxiety levels can rise generally from this cycle.
Understanding nicotine withdrawal
People who stop using nicotine sometimes go through a range of withdrawal symptoms, including:
- Tobacco-based cravings
- Restlessness
- Fear
- Having trouble focusing
- Movement
- Improved hunger
Usually starting in the first few days of abstinence, these symptoms peak; however, following periods, they progressively fade over time.
Though cravings and increased appetite may last longer, nicotine withdrawal symptoms usually peak in the first week and diminish within a month. Many people turn to nicotine to help with stress; thus, anxiety during withdrawal results from both psychological dependence and changes in brain chemistry, like lower dopamine. Without it, especially in cases of known triggers, anxiety sometimes gets worse. Developing efficient plans to control anxiety and preserve long-term smoking cessation depends on an awareness of these biological and psychological aspects.
The connection between anxiety and nicotine use
Because nicotine momentarily raises dopamine and produces a relaxing effect, many people turn to it to help with stress. This relief is fleeting, though, and usually results in withdrawal symptoms including anxiety and irritability, so strengthening reliance. Nicotine use has been connected over time to worsened results in mental health. Research indicates that users—including those of e-cigarettes—have more anxiety and depression than non-users.
Vice versa, stopping smoking has been linked to lowered stress and better mood.
Symptoms, including mood swings and difficulty focusing, make emotional control challenging during withdrawal. People who have poor emotional coping mechanisms sometimes withdraw more severely, which can impede efforts at quitting. Smoking can also affect cognitive reappraisal, a crucial ability for controlling negative emotions, which makes stopping especially difficult. All things considered, even if nicotine might temporarily help, over time, it aggravates mental health problems.2
Coping mechanisms for anxiety and stress during withdrawal
Physical strategies
Exercise
One very effective tool for reducing withdrawal symptoms is consistent physical exercise. For those trying to kick smoking, moderate-intensity exercise has been shown to lower cravings and boost mood. Exercise specifically seems to help reduce withdrawal symptoms by improving mood and lowering smoking urges.
Furthermore, exercise may reduce levels of stress hormones, such as cortisol and adrenaline, thereby lessening cravings and highlighting its possible complementary role in smoking cessation.3
Healthy nutrition
Although there are a few particular studies on the function of nutrition in nicotine withdrawal, general nutritional advice indicates that a balanced diet, high in vital nutrients, can support brain function and mood control. Foods heavy in omega-3 fatty acids, like salmon, and those high in antioxidants, like blueberries, are well-known to boost brain activity and might help control mood swings connected with withdrawal. Moreover, consistent, balanced meals help to maintain steady blood sugar levels, further aiding in avoiding mood swings.
Sleep hygiene
Tied to upsetting sleeping patterns, nicotine withdrawal causes insomnia and more anxiety. Adopting good sleeping habits can help bring balance. Strategies call for a regular bedtime schedule, a comfortable sleeping environment, and avoidance of stimulants like caffeine near bedtime; Additionally, helping to improve sleep quality is a daily regular physical activity.
Psychological strategies
Mindfulness and meditation
Anxiety and stress have been shown to be quite successfully lowered by mindfulness techniques, including Mindfulness-Based Stress Reduction (MBSR) and Mindfulness-Based Cognitive Therapy (MBCT). These methods centre on the present moment and help one to accept ideas and emotions free from evaluation. Additionally, studies have shown that in clinical settings, mindfulness can help people with anxiety and depression.4
Cognitive behavioural techniques (CBT)
One tried-and-true approach for anxiety disorders is cognitive behavioural therapy (CBT). It is mostly concerned with spotting and confronting bad habits and ideas. Meta-analytic studies have found that CBT successfully addresses social anxiety disorder, panic disorder, and generalised anxiety disorder among other anxiety disorders.
Employing better coping strategies and thought patterns, CBT techniques can enable people to control cravings and lower anxiety.5
Journaling
One non-pharmacological tool for helping with mental health management is journaling. Expressive writing helps people to control their emotions, lower their stress levels, and gain an understanding of their actions and thinking patterns. Journaling is extensively used in mental health management, even while evidence-based recommendations are still under development. Studies have also revealed that among participants, journaling can cause emotions of relief, calmness, and lowered stress and anxiety.
Using these psychological techniques helps one control stress and anxiety throughout nicotine withdrawal. Combining mindfulness, CBT strategies, and journaling offers a complete approach to help people negotiate the difficulties of nicotine cessation.
Social and emotional support
Support groups or therapy
Group therapy or individual counselling will greatly enhance results during nicotine withdrawal.
According to studies, group-based behavioural therapy proved to be more successful than self-help or no intervention for smoking cessation. Mutual support and common experiences increase drive and help to lower the relapse rate.
Individual or group forms of Cognitive Behavioural Therapy (CBT) help control emotional triggers driving cravings and anxiety.6
Friends and family involvement
During the quitting process, loved ones' social support offers emotional comfort, useful advice, and responsibility.
A study found that those with supportive non-smoking spouses or social networks were more likely to give up smoking. The study underlined how social contacts help to spread quitting behaviour.
Especially when paired with counselling, family-based interventions have also shown promise in enabling people to stay smoke-free.
Helplines and quitlines
Digital helplines and telephone quitlines provide quick access to expert counselling and tools.
In comparison to those who try on their own, smokers who used telephone counselling through quitlines were twice as likely to successfully quit, according to a study in Tobacco Control.
NHS offer customised assistance, relapse prevention techniques, and can forward calls to nearby programs.
Medical and professional help
Nicotine replacement therapy (NRT)
By delivering tiny, regulated doses of nicotine free of the dangerous chemicals in tobacco smoke, NRT helps ease cravings and withdrawal symptoms.
Compared to placebo or no NRT, all forms of NRT—patches, gum, lozenges, inhalers and nasal sprays—raise the rate of quitting.7
Anti-anxiety medications (if prescribed)
When anxiety becomes severe or incapacitating, doctors may prescribe short-term drugs, including bupropion, an antidepressant approved for smoking cessation that also lessens anxiety and irritability during withdrawal.
According to the New England Journal of Medicine, bupropion doubled the likelihood of a successful quit.
Although used for those with pre-existing anxiety disorders, selective serotonin reuptake inhibitors (SSRIs) should be used carefully and with supervision; as they do help control comorbid anxiety with supervision, but are not the first-line treatments for smoking cessation.8
Working with a mental health professional
Using evidence-based approaches including CBT, motivational interviewing, and relapse prevention planning, mental health professionals—including psychologists and counsellors—offer individualised care.
Combining behavioural counselling with pharmacotherapy greatly increases smoking cessation results.
Particularly in those with co-occurring mental health issues, therapists can customise coping mechanisms for anxiety, teach emotional regulation techniques, and help to prevent relapses.
Long-term strategies for managing anxiety post-withdrawal
Establishing new routines
Establishing disciplined, healthy habits following a smoking cessation helps to fill the void left by nicotine and preserves emotional stability.
By enabling people to replace smoking with better activities, forming implementation intentions around daily activities dramatically increases long-term abstinence.
Establishing consistent routines, such as morning walks, meal preparation, or hobbies, helps one avoid relapse and lessen boredom.9
Identifying and avoiding triggers
Acknowledging circumstances, feelings, or surroundings that set off cravings helps people create coping mechanisms ahead of time.
Particular situations—such as social settings, alcohol use, or stress—often set off cravings. Strategies for avoiding relapse include coping mechanisms, including deep breathing, distraction, and calling a support person.
Long-term success is progressively re-engaging in some triggers under control to develop resistance.10
Building resilience
Resilience is the ability to bounce back from events or stress. Improving it helps one become more capable of managing anxiety in the long term.
Those who have better psychological resilience and emotional control are usually more successful over time in keeping smoking cessation under control and controlling anxiety.
Regular physical exercise, gratitude practice, continuous therapy, and goal setting—that is, activities fostering resilience—are among the ones listed here.
Summary
- Physical and psychological symptoms of nicotine withdrawal abound, most notably anxiety and irritability
- Both biological changes (like lowered dopamine) and the loss of a stress-coping tool drive this anxiety
- Although nicotine might provide temporary relief, over time it compromises mental health
- Withdrawal symptoms can be lessened by coping techniques, including exercise, good sleep, nutrition, mindfulness, and CBT
- Therapy, helplines, NRT, social and professional support all help to increase cessation success.
- Long-term success calls for developing new habits, controlling triggers, and emotional resilience to manage tension free from nicotine
References
- Paolini M, De Biasi M. Mechanistic insights into nicotine withdrawal. Biochemical Pharmacology [Internet]. 2011; 82(8):996–1007. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3312005/.
- Kutlu MG, Gould TJ. Nicotine modulation of fear memories and anxiety: Implications for learning and anxiety disorders. Biochemical Pharmacology. 2015; 97(4):498–511.
- Nur-Hasanah Ruslan, Siti Munira Yasin, Nadzimah Mohd Nasir, Mohamad Rodi Isa. The Impacts of Supervised Exercise Intervention on Tobacco Withdrawal Symptoms. 2023; 16:1179173X2311798–8.
- Brewer JA, Worhunsky PD, Gray JR, Tang Y-Y ., Weber J, Kober H. Meditation experience is associated with differences in default mode network activity and connectivity. Proceedings of the National Academy of Sciences. 2011; 108(50):20254–9.
- Stead LF, Koilpillai P, Fanshawe TR, Lancaster T. Combined pharmacotherapy and behavioural interventions for smoking cessation. The Cochrane database of systematic reviews [Internet]. Chichester, UK: John Wiley & Sons, Ltd; 2016; 3(3):CD008286. Available from: https://www.ncbi.nlm.nih.gov/pubmed/27009521.
- Stead LF, Carroll AJ, Lancaster T. Group behaviour therapy programmes for smoking cessation. Cochrane Database of Systematic Reviews [Internet]. 2017; 3(3). Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6464070/.
- Stead LF, Perera R, Bullen C, Mant D, Hartmann-Boyce J, Cahill K, et al. Nicotine replacement therapy for smoking cessation. Cochrane Database of Systematic Reviews [Internet]. 2012; 11(11). Available from: https://pubmed.ncbi.nlm.nih.gov/23152200/.
- Jorenby DE, Leischow SJ, Nides MA, Rennard SI, Johnston JA, Hughes AR, et al. A Controlled Trial of Sustained-Release Bupropion, a Nicotine Patch, or Both for Smoking Cessation. New England Journal of Medicine. 1999; 340(9):685–91.
- Hagger MS, Hardcastle SJ, Chater A, Mallett C, Pal S, Chatzisarantis NLD. Autonomous and controlled motivational regulations for multiple health-related behaviors: between- and within-participants analyses. Health Psychology and Behavioral Medicine [Internet]. 2014; 2(1):565–601. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346087/.
- Shiffman S, Gwaltney CJ, Balabanis MH, Liu KS, Paty JA, Kassel JD, et al. Immediate antecedents of cigarette smoking: An analysis from ecological momentary assessment. Journal of Abnormal Psychology. American Psychological Association; 2002; 111(4):531–45.
- Kassel JD, Wardle M, Roberts JE. Adult attachment security and college student substance use. Addictive Behaviors. 2007; 32(6):1164–76.







