Boosting Immunity With Raspberries

  • Reem Alamin HassanBachelor's degree, Biomedical Sciences, Queen Mary University of London, UK
  • Richa Lal MBBS, PG Anaesthesia, University of Mumbai, India

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Overview

Raspberries, considered a superfood, are becoming increasingly popular for their potential role in mitigating diseases and their unique nutritional properties. A strong immune system is crucial for maintaining overall health and protecting the body against infections and diseases, and while there are various ways to support immune function, incorporating raspberries into our diets can provide significant benefits due to their immune-boosting properties.

In this article, we will explore the detailed role of raspberries in strengthening the immune system, backed by scientific evidence.

Introduction

The immune system

The immune system is a network of organs, tissues, white blood cells, and molecules which all work together to protect your body from harmful substances that could make you ill.1 It does this by triggering an immune response which is the body’s reaction to foreign invaders, such as bacteria, viruses, and parasites, among other things. The immune system also helps to heal your body from injuries, as well as infections. 

Types of immunity

The immune system’s defence mechanism can be categorised into one of three categories: Innate immunity, adaptive/acquired immunity or passive Immunity. For this article, we will only focus on the first two. 

Innate immunity

Innate immunity is a nonspecific response. It is a first-line defence from any pathogens which might enter the body. It functions through protective barriers, offered by skin and mucous membranes or immune system cells (defence cells) and proteins.2 The skin membranes keep out the majority of the pathogens and the mucous membranes trap them for metabolism by stomach acids and enzymes. 

Adaptive immunity

Adaptive immunity, on the other hand, is a second-line defence mechanism that kicks in if the innate immune system is unable to destroy the pathogens.2 After the initial infection and the body’s innate system triggers a response against the pathogen, the body retains memory of the pathogen.

Upon reinfection, when the adaptive immunity is activated, it can recognise the pathogen, and thus trigger a response against it. It is made up of T-lymphocytes, which signal other immune cells to start the adaptive immune response and detect infected cells, as well as B-lymphocytes which stimulate plasma cells which will produce antibodies. Antibodies are proteins which attach themselves to the foreign invader, targeting it for destruction. 

Image source: Ndinisa Y. BioRender

Importance of a healthy immune system

A healthy immune system plays a crucial role in protecting the body against infections and diseases. 

Here are some key points regarding the importance of a healthy immune system:

Disease prevention: Preventing a disease is often much better than trying to cure it down the line. The immune system is responsible for identifying and neutralising pathogens, such as bacteria, viruses, and parasites, before they can harm the body. A strong immune system can therefore help prevent various infectious diseases.

Efficient healing: When injuries or infections occur, the immune system helps in the healing process by eliminating damaged cells and promoting cell tissue repair. It plays a vital role in wound healing and recovery.

Autoimmune disease prevention: A properly functioning immune system will be able to recognise and differentiate between self (cells belonging to the body) and non-self cells (foreign cells). In autoimmune diseases, the immune system mistakenly attacks the body's own cells, causing chronic inflammation and damage. A healthy immune system reduces the risk of such conditions.

A healthy immune system contributes to overall physical and mental well-being. It helps in maintaining energy levels, improving mood, and reducing the risk of chronic illnesses.

Nutritional profile of raspberries

Raspberries are a nutritious fruit that has an impressive nutritional profile containing vitamins, minerals, and antioxidants. While they do not directly "boost" the immune system, they provide several nutrients that support immune function.

Listed below are some of these nutrients:

High in vitamins and minerals

Vitamin C

Raspberries are an excellent source of vitamin C which is an essential nutrient for immune health. Vitamin C stimulates the production of white blood cells, which are important for fighting off infections and wound healing, and has antioxidant properties. An antioxidant is a compound that protects the cells from damage caused by harmful free radicals (loose electrons) and reduces inflammation, thus supporting immune function.10

Vitamin E

Raspberries also have vitamin E in them which, like vitamin C, has antioxidant properties and may help protect against chronic diseases. 

Manganese

Raspberries are rich in the mineral manganese, which is important for bone health, metabolism, and wound healing.

Rich in antioxidants

Anthocyanins

Raspberries are one of the best dietary sources of anthocyanins, a group of flavonoid compounds that have potent antioxidant and anti-inflammatory effects.

Flavonols

They also contain flavonols, another type of flavonoid with powerful antioxidant properties

Ellagitannins

Raspberries are one of the few natural sources of ellagitannins, a type of polyphenol that has been linked to various health benefits, including reduced inflammation and improved gut health.

Immune-boosting benefits of raspberries

Strengthening the immune response

The role of vitamin C in supporting immune function

Raspberries are a rich source of vitamin C, a powerful antioxidant known for its immune-strengthening properties. Vitamin C enhances various immune functions, including the production and function of white blood cells such as lymphocytes and phagocytes. These cells play a vital role in defending the body against pathogens.3 Studies have shown that vitamin C supplementation can reduce the duration and severity of respiratory tract infections.4

Antioxidants promoting cellular health

Raspberries contain a wide range of antioxidants, including anthocyanins, ellagitannins, and vitamin C. These antioxidants protect cells from loose electrons “free radicals” which damage cells. By preventing damage to cells, these antioxidants promote healthy cellular functioning, including immune cells.5

Fighting oxidative stress

Anthocyanins' protective effects

Anthocyanins, present in raspberry pigments, have been found to possess strong antioxidant and anti-inflammatory properties. They help protect cells from oxidative damage and support overall cellular health. Studies have shown that anthocyanins enhance immune responses, reducing the risk of chronic diseases.6

Ellagitannins' ability to reduce inflammation

Raspberries also contain ellagitannins, which have been studied for their anti-inflammatory effects. Prolonged inflammation can weaken the immune system, increasing vulnerability to infections. By reducing inflammation, ellagitannins contribute to a healthy immune response.7

Supporting gut health

Fibre content aiding digestion and gut microbiome

Raspberries are a good source of dietary fibre, which plays a crucial role in promoting digestive health. A healthy digestive system is essential for overall well-being, including a robust immune system. Additionally, fibre supports the growth of beneficial bacteria in the gut, known as probiotics, which help maintain a balanced gut microbiome. A diverse and well-balanced gut microbiome positively influences immune function.8

Nutrients supporting the growth of beneficial bacteria

Raspberries provide nutrients that support the growth of beneficial bacteria in the gut, such as prebiotics and phytonutrients, which have been shown to have anti-inflammatory and immune-enhancing properties. These compounds act as food for probiotics, enhancing their growth and activity. A healthy gut microbiome is essential for optimal immune function.9

Incorporating raspberries into the diet

Incorporating raspberries into your diet might be an easy way to boost your immune system as they are tasty and easy to add to various meals. 

Fresh raspberries as a snack or topping

Fresh raspberries can make for a delicious and nutritious snack on their own. They are low in calories and packed with fibre, vitamins, minerals, and antioxidants. You can, however, also use them as a topping for yoghurt, oatmeal, or cereal to add a burst of flavour and colour to your meals.

Adding raspberries to smoothies or salads

Raspberries can be a great addition to smoothies. They provide a natural sweetness and vibrant colour to your food. You can blend them with other fruits, yoghurt, or plant-based milk to create a refreshing and nutritious smoothie. In salads, raspberries pair well with leafy greens, nuts, cheese, and vinaigrettes. They can add a lovely balance of tanginess and sweetness to your salads.

Using raspberries as an ingredient in recipes

Raspberries are versatile and can be used in various culinary preparations. They can be incorporated into baked goods like muffins, cakes, and tarts for added flavour, moisture, and nutritional value. Raspberries can also be used in sauces, jams, and coulis for savoury dishes or desserts. Additionally, you can freeze raspberries and use them later for smoothies, sauces, or even homemade popsicles.

Summary

Incorporating raspberries into a balanced diet can significantly contribute to boosting the immune system. Rich in vitamins, antioxidants, and fibre, raspberries strengthen the immune response by enhancing the function of immune cells, fighting oxidative stress, and supporting gut health. 

However, it is important to note that maintaining an overall healthy lifestyle, including regular exercise, adequate sleep, stress management, a varied diet, and avoiding harmful habits like smoking or excessive alcohol consumption, is essential for optimal immune function. So, let us embrace the immune-boosting benefits of raspberries and prioritise their inclusion in our daily diets.

References

  1. How does the immune system work? In: InformedHealth.org [Internet] [Internet]. Institute for Quality and Efficiency in Health Care (IQWiG); 2020 [cited 2023 Nov 16]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK279364/
  2. The innate and adaptive immune systems. In: InformedHealth.org [Internet] [Internet]. Institute for Quality and Efficiency in Health Care (IQWiG); 2020 [cited 2023 Nov 16]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK279396/
  3. Carr A, Maggini S. Vitamin c and immune function. Nutrients [Internet]. 2017 Nov 3 [cited 2023 Nov 16];9(11):1211. Available from: http://www.mdpi.com/2072-6643/9/11/1211
  4. Hemilä H, Chalker E. Vitamin C for preventing and treating the common cold. Cochrane Acute Respiratory Infections Group, editor. Cochrane Database of Systematic Reviews [Internet]. 2013 Jan 31 [cited 2023 Nov 16];2013(5). Available from: http://doi.wiley.com/10.1002/14651858.CD000980.pub4
  5. Rodgers Dinstel R, Cascio J, Koukel S. The antioxidant level of Alaska’s wild berries: high, higher and highest. International Journal of Circumpolar Health [Internet]. 2013 Jan 31 [cited 2023 Nov 16];72(1):21188. Available from: https://www.tandfonline.com/doi/full/10.3402/ijch.v72i0.21188
  6. Salehi B, Sharifi-Rad J, Cappellini F, Reiner Ž, Zorzan D, Imran M, et al. The Therapeutic Potential of Anthocyanins: Current Approaches Based on Their Molecular Mechanism of Action. Front Pharmacol [Internet]. 2020 [cited 2024 Jun 11]; 11:1300. Available from: https://www.frontiersin.org/article/10.3389/fphar.2020.01300/full
  7. Seeram NP. Berry fruits for cancer prevention: current status and future prospects. J Agric Food Chem [Internet]. 2008 Feb [cited 2023 Nov 16];56(3):630–5. Available from: https://pubs.acs.org/doi/10.1021/jf072504n
  8. Gensollen T, Iyer SS, Kasper DL, Blumberg RS. How colonization by microbiota in early life shapes the immune system. Science [Internet]. 2016 Apr 29 [cited 2023 Nov 16];352(6285):539–44. Available from: https://www.science.org/doi/10.1126/science.aad9378
  9. Gibson GR, Hutkins R, Sanders ME, Prescott SL, Reimer RA, Salminen SJ, et al. Expert consensus document: The International Scientific Association for Probiotics and Prebiotics (Isapp) consensus statement on the definition and scope of prebiotics. Nat Rev Gastroenterol Hepatol [Internet]. 2017 Aug [cited 2023 Nov 16];14(8):491–502. Available from: https://www.nature.com/articles/nrgastro.2017.75
  10. Ponder A, Hallmann E. The nutritional value and vitamin C content of different raspberry cultivars from organic and conventional production. Journal of Food Composition and Analysis [Internet]. 2020 Apr [cited 2023 Nov 16];87:103429. Available from: https://linkinghub.elsevier.com/retrieve/pii/S0889157519313432

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This content is purely informational and isn’t medical guidance. It shouldn’t replace professional medical counsel. Always consult your physician regarding treatment risks and benefits. See our editorial standards for more details.

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Yogi Chelsea Ndinisa

Honors in Pharmacology, University of Pretoria, South Africa

Hello, I'm Yogi Chelsea Ndinisa, a dedicated and passionate human physiology graduate with a strong interest in medical communications. My journey into the world of medical writing stems from a diverse educational background and a genuine desire to bridge the gap between scientific knowledge and public understanding. As someone who deeply values effective communication, I believe that translating complex medical concepts into accessible and engaging content is crucial for empowering individuals to make informed decisions about their health.

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