Introduction
When inflammation occurs within the sinuses, the condition is referred to as sinusitis. The National Institute for Health and Care Excellence (NICE) estimates acute sinusitis as one of the most commonly diagnosed conditions in 2–10% of primary care visits, and chronic sinusitis affects 5–12% of the general population.
Sinusitis is chronic in many instances; therefore, many individuals may have lifelong symptoms.1 Such inflammation is typically caused by viral infections. However, sinus infections can also be bacterial.
The sinuses are connected to the ears, i.e., the middle ears, by the eustachian tube, which is commonly referred to as the E-tube. Therefore, any infection in either ear or the sinuses can affect the other.
For instance, middle ear infections can result in thrombosis within the sinuses and have been demonstrated in conditions such as Lemierre syndrome.2 Also, sinusitis can lead to swelling within the E-tube, potentially damaging the middle ear. Therefore, sinusitis can be linked to ear damage and infections.3
During infections, similar microorganisms were found in the sinuses and the ear(s).4
The main factor that differentiates sinus and ear infections is the main symptom: pain intensity and its origin. Sinus infections commonly lead to less pain in the ears, while the pain is intense during ear infections. On the other hand, sinus infections typically lead to more pain in the nose as well as the eyes, alongside headaches.5
As aforementioned, sinusitis can lead to ear infections. It is important to differentiate between sinus and ear infections when diagnosing patients. This article will explore the link between sinus and ear infections, treatment, and prevention strategies.
Understanding sinusitis
Sinusitis is the inflammation and swelling that occurs in the sinuses because of infections, viral or bacterial. The respiratory mucous membranes that line the sinuses undergo inflammation following an infection.6
Allergens such as certain types of airborne fungi and other allergens can also cause allergic sinusitis, which leads to more people presenting with sinusitis who are known to have allergies in comparison with those without allergies.7 Environmental factors, like certain gases and fumes, have been shown to contribute to the development of chronic rhinosinusitis, as they are known to disturb the sinus and nasal passages, causing them to be inflamed and swollen for a long time.8
Sinusitis is characterised into different categories, which are acute, subacute, chronic, and recurrent.
Acute sinusitis
Acute sinusitis is caused by bacterial and viral infections. The symptoms last for a relatively short amount of time, ending in less than four weeks.
Subacute sinusitis
When the symptoms last between four and eight weeks, the sinusitis is said to be subacute. However, it is debated whether the maximum duration the symptoms last for is eight or twelve weeks.
Chronic sinusitis
The condition is chronic when the symptoms persist for more than eight or twelve weeks.
Recurrent sinusitis
The condition is recurrent sinusitis when acute episodes of sinusitis occur multiple times a year.
Fungi and bacteria typically contribute to chronic and recurrent sinusitis.9 Symptoms include, but are not limited to, pain in the face accompanied by pressure as well as nasal discharge and obstruction. Headaches are also a common symptom of this condition.10
Connection between sinusitis and ear infections
The middle ear region and the sinuses are connected by the eustachian tube, as mentioned previously. Sinus infections negatively affect the E-tube function owing to its inflammation and swelling.
The purpose of the E-tube is to protect the middle ear from pressure changes; however, the equilibrium is disturbed when sinus infections occur.11 Sinus inflammation decreases ear function due to the E-tube losing its functionality.12 Sinus congestion is known to cause blockage of the eustachian tube, and when this occurs, the middle ear fills with fluid, causing a negative middle ear pressure value which is linked to the likelihood of viral and bacterial infections. A blocked E-tube from sinus infections increases the susceptibility to ear and sinus infections.13
Sinusitis increases the chance of ear infections due to the sinuses and ears being linked; hence, this is a major cause for concern in children who develop sinusitis.
Symptoms overlap between sinus and ear infections
There are similarities and differences in symptoms observed during sinus and ear infections. Both sinusitis and otitis (middle ear infections) cause negative pressure within the eustachian tube, and inflammation pressure–pressure from swelling that affects the ears and the face
Hearing may also be muffled due to the pressure changes observed during sinusitis. Therefore, this is another shared symptom.14 Headaches are a very common shared symptom known to affect those with sinus and ear infections; dizziness can also accompany these headaches.5
However, some symptoms exclusive to sinus infections are:
- Facial pain and sinus tenderness: These symptoms can be observed in acute sinusitis. Hence, facial packs are commonly utilised to drain mucus15
- Nasal discharge is another symptom that is mainly only observed during sinus infection
Although sinus infections can result in muffled hearing, hearing loss as well as pain in the ears is typically only observed during ear infections and can be caused by viruses that range greatly in severity. Fevers also distinguish sinus and ear infections, as they are mainly seen during the latter type.16
Risk factors and populations more susceptible
There are some populations that are more susceptible to sinusitis, and certain risk factors increase the likelihood of this condition.
Children, for example, have shorter eustachian tubes as they are not developed, which increases the likelihood of middle ear and sinus infections. Also, the likelihood of upper respiratory tract infections is higher in children compared to adults, which leads to E-tube dysfunction; therefore, children are at a particularly high risk regarding sinusitis.17
As mentioned previously, acute episodes of sinusitis three or more times a year make an individual more prone to recurrent sinusitis from inflamed sinuses. Individuals with this condition are more susceptible to inflammation leading to sinusitis.18 People with allergies are also at high risk of sinusitis; airborne allergens, such as pollens and fungi, lead to more sinus infections and allergic sinus disease in this group of individuals.
Sinus and ear infections are exacerbated when allergens are involved. Therefore, the environment can be a key risk factor for sinusitis development.7
Diagnosis and treatment
Diagnosis of sinusitis
There are several ways to diagnose and treat sinus and ear infections for those affected. Physical examinations are widely utilised to determine whether individuals have sinus and ear infections. However, they are not always useful in differentiating between upper respiratory tract infections and sinusitis.18
The symptoms that are presented are a very good way to elucidate whether sinus or ear infections have occurred. Some symptoms are shared, but the characteristic symptoms for each infection type are valuable when diagnosis occurs.
Imaging techniques such as radiography and metrics such as measuring sinus opacity and analysing fluid within the sinuses are also a good way of diagnosing sinusitis and are typically utilised when the aforementioned diagnosing techniques do not work.19
Treatment of sinusitis
Although many acute sinusitis cases resolve themselves, antibiotics are very useful in treating bacterial infections that affect the sinuses and ears.20 Nasal sprays are also used to manage symptoms and are used to reduce swelling within the nasal passages and sinuses.
Ear drops and antibiotics are used for ear infections. However, in the most severe cases, myringostomy tubes, also known as ear tubes, can be inserted into the ear to reduce fluid accumulation, particularly in the middle ear region.21
To effectively reduce the future likelihood of these conditions, preventative strategies such as managing previous sinus conditions and allergies, and good general hygiene are essential.
Summary
Sinus and ear infections are linked due to the anatomy of the sinuses and ears and how they are connected via the eustachian tube. Sinus infections can lead to ear infections when this tube is inflamed and vice versa. Hence, many individuals present symptoms that correspond to sinus and ear infections. In order to prevent complications as a result of sinusitis, it is important to treat symptoms as soon as possible through treatments including antibiotics, nasal sprays, and eardrops. Preventative measures are the best way to prevent complications from sinus and ear infections. When the symptoms for this condition are severe or are suspected to be chronic, medical attention should be sought immediately. This will ensure that in the long term, sinus and ear infections are less prevalent and that sinusitis is easier to manage and will become less of an issue in the near future.
References
- Rosenfeld RM, Andes D, Neil B, Cheung D, Eisenberg S, Ganiats TG, et al. Clinical practice guideline: Adult sinusitis. Otolaryngol – Head Neck Surg [Internet]. 2007 Sep [cited 2024 Oct 04];137(S3). Available from: https://aao-hnsfjournals.onlinelibrary.wiley.com/doi/10.1016/j.otohns.2007.06.726
- Le Monnier A, Jamet A, Carbonnelle E, Barthod G, Moumile K, Lesage F, et al. Fusobacterium necrophorum middle ear infections in children and related complications: report of 25 cases and literature review. Pediatric Infectious Disease Journal [Internet]. 2008 Jul [cited 2024 Oct 04];27(7):613–7. Available from: https://journals.lww.com/00006454-200807000-00006
- Choi KY, Jang S, Seo G, Park S-K. Effect of endoscopic sinus surgery on Eustachian tube function in adult sinusitis patients: a prospective case-control study. Journal of Clinical Medicine [Internet]. 2021 [cited 2024 Oct 04];10(20):4689.Available from: https://www.mdpi.com/2077-0383/10/20/4689
- Brook I. Microbiology of sinusitis. Proceedings of the American Thoracic Society [Internet]. 2011 [cited 2024 Oct 04];8(1):90-100. Available from: https://www.atsjournals.org/doi/full/10.1513/pats.201006-038rn
- Moran D, Sutjita M, Daretany K. Conjunctivitis, Otitis, and Sinusitis. In Infection Management for Geriatrics in Long-Term Care Facilities [Internet]. 2006 Sep 14 [cited 2024 Oct 04];(pp. 369-382). CRC Press. Available from: https://www.taylorfrancis.com/books/9781420021110
- Kaliner MA. Human nasal host defense and sinusitis. Journal of Allergy and Clinical Immunology [Internet]. 1992 [cited 2024 Oct 04];90(3):424-30. Available from: https://www.jacionline.org/article/0091-6749(92)90162-U/pdf
- Spector SL. The role of allergy in sinusitis in adults. Journal of Allergy and Clinical Immunology [Internet]. 1992 [cited 2024 Oct 04];90(3):518-20. Available from: https://www.jacionline.org/article/0091-6749(92)90178-5/pdf
- Alkholaiwi FM, Almutairi RR, Alrajhi DM, Alturki BA, Almutairi AG, Binyousef FH. Occupational and environmental exposures, the association with chronic sinusitis. Saudi Medical Journal [Internet]. 2022 [cited 2024 Oct 04];43(2):125. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC9127924/pdf/SaudiMedJ-43-2-125.pdf
- Leung RS, Katial R. The diagnosis and management of acute and chronic sinusitis. Primary care: Clinics in office practice [Internet]. 2008 [cited 2024 Oct 04];35(1):11-24. Available from: https://linkinghub.elsevier.com/retrieve/pii/S009545430700084X
- Rosenfeld RM. Acute sinusitis in adults. New England Journal of Medicine [Internet]. 2016 [cited 2024 Oct 04];375(10):962-70. Available from: https://www.bristolctoralsurgery.com/files/2017/02/adult-sinusitis-management.pdf
- Makibara RR, Fukunaga JY, Gil D. Eustachian tube function in adults with intact tympanic membrane. Brazilian Journal of Otorhinolaryngology [Internet]. 2010 [cited 2024 Oct 04];76(3):340-6. Available from:https://www.sciencedirect.com/science/article/pii/S1808869415304171
- Bakhshaee M, Ardakani HP, Ghazizadeh AH, Movahed R, Jarahi L, Rajati M. Middle ear function in sinonasal polyposis. European Archives of Oto-Rhino-Laryngology [Internet]. 2016 [cited 2024 Oct 04];273:2911-6. Available from: https://link.springer.com/article/10.1007/s00405-015-3812-5
- Alper CM, Teixeira MS, Swarts JD. Eustachian tube function in adults with ventilation tubes inserted for otitis media with effusion. The Journal of International Advanced Otology [Internet]. 2018 [cited 2024 Oct 04];14(2):255. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC6354449/
- Islam MZ, Akram MS, Mahmud M, Sarker MS, Hasan M, Rahman MA, et al. Otological Presentation of Obstructive Nasal Lesions: A Study of 50 Cases. Bangladesh Journal of Otorhinolaryngology [Internet]. 2021 [cited 2024 Oct 04];27(2):159-69. Available from:https://banglajol.info/index.php/BJO/article/view/56363
- Worrall G. Acute sinusitis. Canadian Family Physician [Internet]. 2011 [cited 2024 Oct 04];57(5):565-7. Available from: https://www.cfp.ca/content/57/5/565.short
- Cohen BE, Durstenfeld A, Roehm PC. Viral causes of hearing loss: a review for hearing health professionals. Trends in hearing [Internet]. 2014 [cited 2024 Oct 04];18:2331216514541361. Available from: https://journals.sagepub.com/doi/full/10.1177/2331216514541361
- Goulioumis AK, Gkorpa M, Athanasopoulos M, Athanasopoulos I, Gyftopoulos K. The Eustachian tube dysfunction in children: anatomical considerations and current trends in invasive therapeutic approaches. Cureus [Internet]. 2022 [cited 2024 Oct 04];14(7). Available from:https://assets.cureus.com/uploads/review_article/pdf/92025/20220823-1137-1miqayv.pdf
- Shaikh N, Hoberman A, Kearney DH, Colborn DK, Kurs-Lasky M, Jeong JH, et al. Signs and symptoms that differentiate acute sinusitis from viral upper respiratory tract infection. The Paediatric Infectious Disease Journal [Internet]. 2013 [cited 2024 Oct 04];32(10):1061-5. Available from: https://journals.lww.com/pidj/abstract/2013/10000/signs_and_symptoms_that_differentiate_acute.6.aspx
- Engels EA, Terrin N, Barza M, Lau J. Meta-analysis of diagnostic tests for acute sinusitis. Journal of Clinical Epidemiology [Internet]. 2000 [cited 2024 Oct 04];53(8):852-62. Available from: https://www.sciencedirect.com/science/article/abs/pii/S0895435600002092
- Blin P, Blazejewski S, Lignot S, Lassalle R, Bernard MA, Jayles D, et al. Effectiveness of antibiotics for acute sinusitis in real‐life medical practice. British Journal of Clinical Pharmacology [Internet]. 2010 [cited 2024 Oct 04];70(3):418-28. Available from: https://bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/j.1365-2125.2010.03710.x
- Grote J, Kuijpers W. Middle ear effusion and sinusitis. The Journal of Laryngology & Otology [Internet]. 1980 [cited 2024 Oct 04;94(2):177-83. Available from: https://www.cambridge.org/core/journals/journal-of-laryngology-and-otology/article/abs/middle-ear-effusion-and-sinusitis/4ECDC18983DB4CCF13BCFAE4CD496DFB

