Disconnected: The Experience Of Depersonalisation Derealisation Disorder
Published on: September 24, 2024
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Rita Evans

Rita is a first-class Biology BSc graduate and Neuroendocrinology PhD candidate, with a passion for translating intricate scientific information into clear and engaging content. Drawing on her experience in pharmacy and clinical trials, Rita brings a detailed understanding of complex medical concepts to her role as a medical writer.

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Mithuna Chethiparambil Prasanth

Bachelor of Science - BS, Biology/Biological Sciences, General, Oxford Brookes University

Introduction

Have you ever felt disconnected from yourself or your surroundings? If you deal with persistent or recurrent feelings of unreality and detachment, you may be dealing with depersonalisation derealisation disorder (DPDR). While you may feel afraid or confused by these feelings, around 1% of the population are thought to experience this disorder, so you are not alone.1

Overview: DPDR

DPDR is a dissociative disorder, which causes an individual to feel detached or unreal, patients have described feeling as if they are “living in a dream” or “like a robot”.2 A person with DPDR may experience only depersonalisation, only derealisation or a mixture of both of these dissociative symptoms.

  • Depersonalisation is the feeling of being detached from oneself. A person experiencing depersonalisation may feel disconnected from their thoughts, actions, or bodies. They can also feel like they are watching themselves from the outside
  • Derealisation is the feeling of being detached from one’s surroundings. The world and people around may appear foggy, lifeless, dreamlike or unreal

It can be a very distressing experience and can last anywhere from a few minutes to many years. Some people with the condition may fear that they have developed psychosis or schizophrenia, but there are some distinct differences.

While those suffering from a psychotic episode may experience dissociation, they will likely experience additional symptoms, such as hallucinations (seeing, hearing, tasting or feeling things that aren’t really there) and delusions, for example, the unshakeable belief that someone or something is trying to kill them.

Causes of DPDR

Dissociation can be triggered by stressful or traumatic events, for example:3

  • Physical, sexual or emotional abuse
  • Neglect/abuse during childhood
  • War or kidnapping
  • An invasive medical procedure
  • The death of a loved one

Additionally, DPDR is often comorbid with other mental health issues, such as:4

Drug use can also lead to dissociative symptoms.8 For example, marijuana use can lead to temporary symptoms of DPDR, which generally subside within 2 hours, however, these symptoms have been known to last months or years in some cases.9 This is particularly true for individuals using marijuana during or after a stressful or traumatic experience, who appear to be more at risk of developing marijuana-induced DPDR.10

However, in some instances, DPDR symptoms can occur as a result of physical problem called vestibular dysfunction. The vestibular (or inner ear) system controls coordination and balance. Therefore, issues with this system, such as vestibular neuritis, can result in feelings of dizziness and vertigo. This disorientation, and consequent anxiety, can lead to symptoms of DPDR.11

Treatments for DPDR

The good news is that DPDR is treatable. The main treatment options are medications or psychotherapy. Research suggests that in terms of drug treatments, selective serotonin reuptake inhibitors (SSRIs) and lamotrigine may be helpful, however, medications are not considered to be the best option. Psychotherapy is widely accepted to be the most beneficial treatment, this can include:12

  • Cognitive behavioural therapy (CBT)
  • Mindfulness-based cognitive therapy (MBCT)
  • Psychoanalytic therapy
  • Psychoanalysis combined with abreaction (reliving the traumatic event in a safe, therapeutic setting)

Treatment for those with vestibular dysfunction will vary depending on their specific issue, but physiotherapy with an inner ear specialist physiotherapist is commonly used to help reduce or eliminate symptoms.13

FAQs

IS DPDR the same as psychosis?

No, although psychosis and DPDR can share feelings of dissociation, psychosis has the additional symptoms of hallucinations and/or delusions.

Is DPDR permanent?

No, DPDR can be treated and complete recovery is possible.

Summary

DPDR is a distressing, but relatively common, dissociative disorder that causes persistent or recurring feelings of detachment from oneself or one’s surroundings. It can be triggered by stress, trauma, drug use, or vestibular dysfunction, and is often comorbid with other mental health issues. Thankfully, DPDR does not have to be permanent and is usually treated with psychotherapy or, in the case of vestibular issues, physiotherapy.

References

  1. Yang J, Millman LSM, David AS, Hunter ECM. The prevalence of depersonalization-derealization disorder: a systematic review. Journal of Trauma & Dissociation [Internet]. 2023 Jan 1 [cited 2024 Apr 24];24(1):8–41. Available from: https://www.tandfonline.com/doi/full/10.1080/15299732.2022.2079796
  2. Wang S, Zheng S, Zhang FX, Ma R, Feng S, Song M, et al. The treatment of depersonalization-derealization disorder: a systematic review. Journal of Trauma & Dissociation [Internet]. 2024 Jan [cited 2024 Apr 24];25(1):6–29. Available from: https://www.tandfonline.com/doi/full/10.1080/15299732.2023.2231920
  3. Murphy RJ. Depersonalization/derealization disorder and neural correlates of trauma-related pathology: a critical review. Innov Clin Neurosci [Internet]. 2023 [cited 2024 Apr 24];20(1–3):53–9. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10132272/
  4. Lyssenko L, Schmahl C, Bockhacker L, Vonderlin R, Bohus M, Kleindienst N. Dissociation in psychiatric disorders: a meta-analysis of studies using the dissociative experiences scale. AJP [Internet]. 2018 Jan [cited 2024 Apr 24];175(1):37–46. Available from: https://ajp.psychiatryonline.org/doi/full/10.1176/appi.ajp.2017.17010025
  5. Armour C, Karstoft KI, Richardson JD. The co-occurrence of PTSD and dissociation: differentiating severe PTSD from dissociative-PTSD. Soc Psychiatry Psychiatr Epidemiol [Internet]. 2014 Aug 1 [cited 2024 Apr 24];49(8):1297–306. Available from: https://doi.org/10.1007/s00127-014-0819-y
  6. Tatlı M, Cetinkaya O, Maner F. Evaluation of relationship between obsessive-compulsive disorder and dissociative experiences. Clin Psychopharmacol Neurosci [Internet]. 2018 May [cited 2024 Apr 24];16(2):161–7. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953015/
  7. Hunter ECM, Sierra M, David AS. The epidemiology of depersonalisation and derealisation. Soc Psychiatry Psychiatr Epidemiol [Internet]. 2004 Jan 1 [cited 2024 Apr 24];39(1):9–18. Available from: https://doi.org/10.1007/s00127-004-0701-4
  8. Ricci V, Maina G, Martinotti G. Dissociation and temporality in substance abuse: a clinical phenomenological overview. Psychopathology [Internet]. 2023 Oct 30 [cited 2024 Apr 24];1–10. Available from: https://karger.com/doi/10.1159/000533862
  9. Madden SP, Einhorn PM. Cannabis-induced depersonalization-derealization disorder. American Journal of Psychiatry Residents’ Journal [Internet]. 2018 Feb [cited 2024 Apr 24];13(2):3–6. Available from: https://psychiatryonline.org/doi/10.1176/appi.ajp-rj.2018.130202
  10. Madden SP, Einhorn PM. Cannabis-induced depersonalization-derealization disorder. AJP Residents’ Journal [Internet]. 2018 Feb [cited 2024 Apr 25];13(2):3–6. Available from: https://psychiatryonline.org/doi/10.1176/appi.ajp-rj.2018.130202
  11. Elyoseph Z, Geisinger D, Zaltzman R, Gordon CR, Mintz M. How vestibular dysfunction transforms into symptoms of depersonalization and derealization? Journal of the Neurological Sciences [Internet]. 2023 Jan 15 [cited 2024 Apr 25];444:120530. Available from: https://www.sciencedirect.com/science/article/pii/S0022510X22003926
  12. Mishra S, Das N, Mohapatra D, Mishra BR. Mindfulness-based cognitive therapy in depersonalization-derealization disorder: a case report. Indian Journal of Psychological Medicine [Internet]. 2022 Nov [cited 2024 Apr 24];44(6):620–1. Available from: http://journals.sagepub.com/doi/10.1177/02537176211040259
  13. Treatment for vestibular disorders. J Neurol Phys Ther [Internet]. 2016 Apr [cited 2024 Apr 25];40(2):156. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795095/
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Rita Evans

Rita is a first-class Biology BSc graduate and Neuroendocrinology PhD candidate, with a passion for translating intricate scientific information into clear and engaging content. Drawing on her experience in pharmacy and clinical trials, Rita brings a detailed understanding of complex medical concepts to her role as a medical writer.

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