Overview
Dry eyes cause discomfort by impairing normal vision, when using the computer, reading or driving a vehicle.1Dry eyes are divided into many types; aqueous deficient dry eye, evaporative dry eye, and mixed dry eye.1
Aqueous dry eye is caused by a lack of liquid water secretion in tears by the lacrimal glands within the eye, leading to the film coating of the eye becoming dry.1,2 Evaporative dry eye is caused by a lack of oil secretion by the Meibomian glands leading to tear dissipation.1,2 This oil prevents dehydration of the eyes by retaining water usually secreted in tears.1,2
This article seeks to;
- Discuss dry eye signs and symptoms, determinants, and diagnosis
- Discuss treatment options (home remedies, prescribed and over-the-counter treatments)
- Discuss prevention methods
Dry eyes signs and symptoms
Signs and symptoms of dry eyes include;1,2
- Burning sensation
- Sharp tingling sensation
- Red, bloodshot appearance
- Itchiness (pruritus)
- Sensitivity to light (photophobia)
- The feeling of a foreign object lodged inside the eye
- Eyelid margin pain with swelling (edema), burning, redness, and itchiness (blepharitis)
- Blurred vision
Dry eyes risk factors
Risk factors which predispose individuals to dry eyes include;1,2
- Overuse of electronic devices due to blue light emitting from the screens
- Having undergone a stem cell transplant
- Allergen exposure (e.g. pollen, dust, animal fur, urine, shredded skin and saliva)
- Diseases such as collagen vascular disease, diabetes, Sjögren’s syndrome, hepatitis C virus, sarcoidosis, and HIV/HTLV1
- Individuals who were assigned female at birth (AFAB)
- Older/Elderly individuals
- Having undergone corneal refractive, cataract surgery with a large slit made in the eye, or corneal transplant surgery
- Deficiency of vitamin A
- Deficiency of androgen in menopause
- Oestrogen therapy after menopause
- Radiation therapy and chemotherapy for cancer treatment
- Prescribed medications such as antihistamines, isotretinoin, beta-blockers, antidepressants, and diuretics
- Less moisture in the air
- Ovary dysfunction
- Smoking
Diagnosis methods
To diagnose dry eyes, medical health professionals will sequentially;
- Check patient history for diagnosis of medical health conditions1
- Ask the patient their symptoms and their severity through questionnaires1
- Check the time, location, and seasonal variation of their symptoms occurrence (for instance in spring and autumn, allergen content in the air is higher which causes dry eyes in those with sensitivity to allergens)1
- Check the stability of the tear film on the outer surface of the eye using a stain called fluorescein1,2
- Corneal staining using fluorescein/lissamine green1,2
- Carry out a Schirmer test to determine the level of tear secretion1
- Examine eyelid margins and Meibomian gland openings1
Treatment
Lifestyle modifications to reduce dry eyes
- Decreasing electronic device screen time use and taking regular breaks in between
- Consuming vitamin A-rich foods (e.g. cantaloupe, kale, broccoli, spinach, carrots, sweet potatoes)3
- Consuming omega-3 fatty acid-rich foods (e.g. fish, nuts, and seeds) to reduce eye inflammation in dry eyes1
- Taking fish oil liquid/oral supplements1
Over-the-counter treatments to relieve dry eyes
- Eye drops containing lipids, vitamin E, and glycerine which moisturise and soothe dry eyes1,2
- Artificial tears ( gel or ointment)1,2
- Eye sprays and mists (key ingredients to moisturise and soothe dry eyes include lipids and lubricants)1,2
Prescribed treatments for dry eyes
An ophthalmologist, pharmacist and/or optician may prescribe;
- Anti-inflammatory medications such as topical corticosteroids to treat redness, swelling, pain, and loss of function1
- Intense pulsed light (IPL) therapy improves Meibomian gland oil secretion by increasing tear production and reduces inflammatory immune molecules by raising the temperature of the skin in the eyelid and around the eye which increases the secretion of oil-containing lipids, to rehydrate dry eyes4
- Collagen/silicone plugs block or decrease the flow of tear drainage in the eyes, to retain tears for hydration1
- LipiFlow® treatment provides safe heat temperatures and mechanical stimulation to inner eyelids to unclog and improve the Meibomian glands' function, and allow oil secretion for retaining tear film stability which reduces tear evaporation5
- Eye drops tailored to patient severity of signs, symptoms, medical history, and type of dry eye1,2
Home remedies to reduce dry eyes
- Using warm compresses on your eyes - soak a clean cloth in warm water, wring out extra water and place the compress on the eye for as long as it is warm2
- Adding moisture to the air with a humidifier2
- Blinking exercises2
- Thermal and massage treatments stimulate the Meibomian gland to secrete oils to prevent tear evaporation and promote hydration, lubrication, and moisturisation of dry eyes5,6
Prevention strategies
- Visiting opticians frequently for regular eye checkups
- Taking regular breaks and blinking frequently when using screens (i.e. phones, computers, tablets and televisions)2
- Drinking 6-8 glasses of water a day to ensure sufficient hydration of the eyes
- Managing diagnosed medical conditions which may cause dry eyes as a symptom by scheduling regular appointments with the doctor1,2
- Staying inside when pollen levels are higher in spring and washing hands after exposure to pet or plant allergens
- Quit smoking7
FAQs
What are the two main causes of dry eyes?
There are multiple causes of dry eyes which include but are not limited to; environment/pet-based allergen exposure, excessive air flow/air conditioning, excessive use of electronic devices without regular breaks, taking certain medications, being diagnosed with diseases in which dry eyes may occur as a symptom and lower androgen levels during menopause.1,2
How do you reduce dry eye symptoms?
Eating a balanced diet will ensure adequate macronutrients and micronutrients are consumed (vitamin A and omega-3 fatty acid-rich food is great for eye health), quitting smoking, limiting electronic device use, blinking regularly and taking frequent breaks when using electronic devices, using a humidifier, and managing conditions which cause dry eyes by visiting a doctor/optician/pharmacist regularly will help.1,2 Secondly, using non-prescription lubricating eye drops, eye mists, and sprays also helps to soothe dry eyes.1,2
Summary
To summarise, a range of risk factors can cause dry eyes. Diagnosis of dry eyes is determined via visits to the optician, ophthalmologist and/or pharmacist, who conduct a series of eye tests to elucidate the severity and type of signs and symptoms. The tests usually involve examining water and oil secretion levels in tears, the stability of the tear film, and checking whether the Meibomian and lacrimal glands' function may be blocked/limited in their secretory ability. Treatments combine home remedies, over-the-counter medications, and prescribed treatments by medical health professionals. Prevention methods include regular eye health examinations, managing health conditions that may cause dry eyes as a symptom, reducing electronic device use, blinking frequently, and quitting smoking amongst many options.
References
- Messmer EM. The Pathophysiology, Diagnosis, and Treatment of Dry Eye Disease. Dtsch Arztebl Int [Internet]. 2015 [cited 2024 Apr 18]; 112(5):71–82. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335585/.
- Golden MI, Meyer JJ, Patel BC. Dry Eye Syndrome. Treasure Island (FL): StatPearls PublishingStatPearls [Internet]. 2024 [cited 2024 Apr 18]. Available from: http://www.ncbi.nlm.nih.gov/books/NBK470411/.
- Gilbert C. What is vitamin A and why do we need it? Community Eye Health [Internet]. 2013 [cited 2024 Apr 18]; 26(84):65. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936685/.
- Barbosa Ribeiro B, Marta A, Ponces Ramalhão J, Marques JH, Barbosa I. Pulsed Light Therapy in the Management of Dry Eye Disease: Current Perspectives. Clin Ophthalmol [Internet]. 2022 [cited 2024 Apr 18]; 16:3883–93. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9703996/.
- Zhao Y, Veerappan A, Yeo S, Rooney DM, Acharya RU, Tan JH, et al. Clinical Trial of Thermal Pulsation (LipiFlow) in Meibomian Gland Dysfunction With Preteatment Meibography. Eye Contact Lens [Internet]. 2016 [cited 2024 Apr 18]; 42(6):339–46. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098463/.
- Wang MTM, Feng J, Wong J, Turnbull PR, Craig JP. Randomised trial of the clinical utility of an eyelid massage device for the management of meibomian gland dysfunction. Cont Lens Anterior Eye [Internet]. 2019 [cited 2024 Apr 18]; 42(6):620–4. Available from: https://pubmed.ncbi.nlm.nih.gov/31358441/
- Donthineni PR, Shanbhag SS, Basu S. An Evidence-Based Strategic Approach to Prevention and Treatment of Dry Eye Disease, a Modern Global Epidemic. Healthcare (Basel) [Internet]. 2021 [cited 2024 Apr 18]; 9(1):89. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7830429/.

