Heart-Healthy Benefits Of Incorporating Guava Into Your Diet

  • Muna Hassan Bachelor of science in molecular biology and Genetics Üsküdar Üniversitesi

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Introduction

Guava (Psidium guajava L.) from the Myrtaceae family is renowned for its diverse nutritional composition, especially in its leaves. The content analysis reveals a rich array of essential compounds, including potassium, phosphorus, nitrogen, ascorbic acid, carbohydrates, phenols, and sulphates. These constituents contribute to guava's reputation as a valuable dietary resource.1

A recent study revealed some exciting news about a popular fruit juice guava fruit juice and its potential benefits for our heart health. For the first time, researchers found that guava juice can help reduce platelet aggregation, a process that can contribute to cardiovascular issues. Guava fruit juice seems to have its unique way of promoting heart health. This study highlights guava fruit juice and its promising cardiovascular benefits, providing us with another reason to enjoy these tasty and heart-friendly beverages.2

Vitamin C and guava 

Vitamin C plays a crucial role in regulating how our bodies handle cholesterol, which is important for heart health. Studies in animals like guinea pigs, rabbits and rats have shown that vitamin C influences how our bodies break down cholesterol. In humans, research has found a connection between higher vitamin C intake and lower risk of cardiovascular disease.3 Vitamin C is a nutrient that our bodies need, and guava happens to be a fantastic source of it. This vitamin is essential for our health, and guava's rich content makes it a great addition to our diet.4

Blood pressure support

Researchers investigated the impact of consuming guava fruit on blood pressure and blood lipids in individuals with high blood pressure. They divided 145 participants into two groups: one that included guava in their daily diet and another that stuck to their usual diet. Both groups maintained similar levels of salt, fat, cholesterol, caffeine, and alcohol intake. After four weeks, the group incorporating guava experienced a significant decrease in both systolic and diastolic blood pressure compared to the group following their regular diet. This positive effect is attributed to the increased intake of potassium and soluble dietary fibre found in guava.

Dietary fibre’s impact on reducing LDL cholesterol

Additionally, the guava group showed a reduction in total cholesterol and triglycerides, suggesting potential heart health benefits. Importantly, there was no decrease in the "good" HDL cholesterol, indicating that guava's natural components may contribute to improving heart health without compromising beneficial cholesterol levels. So, incorporating more guava into your diet might offer a tasty way to support your heart and overall well-being.5

Anti-inflammatory effects

Guava leaves (GLs) have been recognized for their health benefits, particularly their antioxidant and anti-inflammatory effects. These properties are attributed to various compounds present in GLs, such as gallic acid, pyrocatechol, taxifolin, ellagic acid, and ferulic acid. These compounds act as antioxidants, helping to combat harmful molecules called free radicals in our bodies.1

Free radicals, produced during metabolic processes, can contribute to various health issues like inflammation, neurological disorders, and more. The antioxidant compounds in GLs, including flavonoids like quercetin and hesperetin, play a crucial role in neutralising these free radicals, minimising their harmful effects. Studies have shown that GL extracts exhibit antioxidant abilities, protecting against oxidative stress and reducing the damage caused by reactive oxygen species (ROS).1

Blood sugar control

Eating guava pulp without the peel might be a tasty way to support your heart health and manage cholesterol levels. A study found that after adding guava pulp to the diet, there wasn't a significant change in fasting blood sugar levels. However, there was a positive impact on cholesterol levels – total cholesterol, triglycerides, and the so-called "bad" LDL cholesterol all decreased significantly. This suggests that enjoying guava pulp without the peel could be good for both your heart and blood sugar. So, incorporating this delicious fruit into your diet might be a simple and enjoyable step toward a healthier you.6

Weight management

GLs are showing promise not just as a tasty treat but also as a potential ally in managing diabetes and cholesterol levels. Studies have found that treating diabetic rats with GLs led to a reduction in blood glucose levels and improved oral glucose tolerance. This is crucial for preventing weight loss caused by impaired carbohydrate metabolism. GLs seem to stabilise insulin levels and enhance the activity of enzymes like hexokinase and G6PDH while reducing the activity of enzymes associated with glucose production.1

Guava leaves as a functional food 

GLs are turning out to be more than just leaves – they're becoming a fantastic addition to our foods, contributing to our health in various ways. Recent articles highlight those leftover parts of fruits and vegetables, like peels, seeds, and leaves, are rich in bioactive compounds that can be used as functional food ingredients. In the case of guava leaves, they contain a bunch of powerful compounds like rutin, naringenin, gallic acid, catechin, and more, known for their antimicrobial, antioxidant, and anti-inflammatory properties.1

Studies show that including guava leaf extract in food can have numerous benefits. For instance, it has been linked to improving vascular dysfunction in mice with obesity-related issues and has been used in making jelly with antioxidant and antimicrobial properties. People even consume guava leaf tea as a functional beverage without worrying about interactions with medications. It's particularly popular among those at risk of developing diabetes. Guava leaves have also found their way into the diets of laying hens, enhancing egg quality by acting against inflammatory pathways.1

In a nutshell, guava leaves are a powerhouse of beneficial compounds that can be added to various foods without compromising their taste or texture. From teas to jellies and even sausages, guava leaves are proving to be a versatile and healthy addition to our diets. So, next time you enjoy something with guava in it, know that you might be getting more than just a delicious flavour – you're giving your body a boost of natural goodness.

Summary 

Nutritional highlights

  • Guava is rich in essential compounds such as potassium, phosphorus, nitrogen, ascorbic acid, carbohydrates, phenols, and sulphates, making it a valuable dietary resource
  • Vitamin C, a crucial nutrient for heart health, is abundant in guava, influencing cholesterol breakdown and showing connections to lower cardiovascular disease risks

Heart health support

  • Research indicates that incorporating guava into the diet significantly lowers both systolic and diastolic blood pressure, attributed to increased potassium and soluble dietary fibre intake

Anti-inflammatory effects

  • Guava leaves (GLs) are recognized for their antioxidant and anti-inflammatory effects, attributed to compounds like gallic acid, pyrocatechol, and flavonoids such as quercetin and hesperetin

Blood sugar control

  • Guava pulp without the peel positively impacts cholesterol levels without significantly affecting fasting blood sugar
  • Enjoying guava pulp becomes a simple and enjoyable step toward supporting heart health and managing blood sugar

Weight management

  • Guava leaves (GLs) show promise in managing diabetes by stabilising insulin levels, improving oral glucose tolerance, and preventing weight loss due to impaired carbohydrate metabolism

Guava leaves as a functional food

  • Guava leaves, rich in bioactive compounds like rutin, naringenin, and gallic acid, are becoming a fantastic addition to various foods

References

  • Kumar, M., Tomar, M., Ryszard Amarowicz, Vivek Saurabh, M. Sneha Nair, Maheshwari, C., Minnu Sasi, Prajapati, U., Hasan, M., Singh, S., Sushil Changan, Rakesh Kumar Prajapat, Berwal, M.K. and Varsha Satankar (2021). Guava (Psidium guajava L.) Leaves: Nutritional Composition, Phytochemical Profile, and Health-Promoting Bioactivities. Foods, [online] 10(4), pp.752–752. doi:https://doi.org/10.3390/foods10040752.
  • Thitiporn Thaptimthong, Thitima Kasemsuk, Nathawut Sibmooh and Supeenun Unchern (2016). Platelet inhibitory effects of juices from Pachyrhizus erosus L. root and Psidium guajava L. fruit: a randomized controlled trial in healthy volunteers. BMC Complementary and Alternative Medicine, [online] 16(1). doi:https://doi.org/10.1186/s12906-016-1255-1.
  • JA, S. (2020). Vitamin C and cardiovascular disease: a review. Journal of the American College of Nutrition, [online] 11(2). Available at: https://pubmed.ncbi.nlm.nih.gov/1578086/ [Accessed 22 Feb. 2024].
  • E.A. Conde Garcia, Nascimento, V.T. and A.B. Santiago Santos (2003). Inotropic effects of extracts of Psidium guajava L. (guava) leaves on the guinea pig atrium. Brazilian Journal of Medical and Biological Research, [online] 36(5), pp.661–668. doi:https://doi.org/10.1590/s0100-879x2003000500014.
  • Singh, R.B., Rastogi, S.S., Singh, R., Ghosh, S. and Niaz, M.A. (1992). Effects of guava intake on serum total and high-density lipoprotein cholesterol levels and on systemic blood pressure. The American Journal of Cardiology, [online] 70(15), pp.1287–1291. doi:https://doi.org/10.1016/0002-9149(92)90763-o.
  • MA; (2022). Can guava fruit intake decrease blood pressure and blood lipids? Journal of human hypertension, [online] 7(1). Available at: https://pubmed.ncbi.nlm.nih.gov/8383769/#:~:text=Dietary%20adherence%20to%20guava%20intake,pressures%20compared%20with%20group%20B. [Accessed 22 Feb. 2024].
  • Kumari, S., R Rakavi and Manaswini Mangaraj (2016). Effect of Guava in Blood Glucose and Lipid Profile in Healthy Human Subjects: A Randomized Controlled Study. Journal of Clinical and Diagnostic Research. [online] doi:https://doi.org/10.7860/jcdr/2016/21291.8425.

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Cherise Dixon

MRes, Life Sciences, Birmingham City University

Cherise is a Biomedical Sciences graduate; she is currently pursuing a Master's in Life Sciences with a focus on researching the effects of drugs in endometrial cancer. Experienced in laboratory work, including roles at NHS Trust and the private sector. As a Scientific Writing Intern at Klarity, she contributes weekly articles which align with a passion for preventive health and a commitment to public well-being.

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