How Do Nutritional Deficiencies Contribute To Symptoms Of Tiredness And Excessive Sweating?
Published on: March 27, 2025
how do nutritional deficiencies contribute to symptoms of tiredness and excessive sweating
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Colette Lawler

BSc Oral Health Science, MSc Health Informatics, Dental Hygienist/Therapist & Freelance Medical Writer

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Velamala Sai Sudha

Doctor of Pharmacy - Dayananda Sagar College of Pharmacy, Bangalore, India

Excessive sweating is medically known as hyperhidrosis. Fatigue is a common term used to describe a state of tiredness. Both of these symptoms can be associated with a variety of health issues. These may include dehydration, lack of sleep, physical activity, low calcium levels, and various other medical conditions. Additionally, factors such as underlying medical conditions, stress, side effects from medications, and nutritional deficiencies can contribute to feelings of tiredness.

Excessive sweating without an obvious reason is known as primary hyperhidrosis, which is believed to stem from an issue related to the nervous system. The exact cause of its development remains unclear. Certain medical conditions, including diabetes, heart failure, anxiety, and an overactive thyroid, are known to trigger excessive sweating. Additionally, deficiencies in vitamins such as vitamin D and vitamin B12 may also lead to this condition.

Fatigue and excessive sweating can be symptoms of different medical issues, but if they arise suddenly, it's important to seek urgent or emergency medical care.

Nutritional deficiencies can cause fatigue and excessive sweating. It is important to identify which specific nutrients are lacking to effectively address these issues. We should consider factors beyond just lifestyle or sleep patterns to understand the root causes of these symptoms.

This article will cover essential nutrients and how they affect fatigue and sweating. It will also explain how nutritional deficiencies relate to other factors.

Nutrition's role in energy and body temperature regulation

Food consists of nutritional components that our bodies break down and convert into energy to maintain proper functioning. The three main components used for energy are proteins, carbohydrates, and fats. The body transforms these components into a substance called adenosine triphosphate (ATP). ATP fuels all cellular functions in the body and must be generated continuously to ensure that all bodily functions operate effectively.

Digestion breaks down the three main components of food—proteins, carbohydrates, and fats—into their simplest forms: amino acids, glucose, and fatty acids. Once these energy compounds are in their basic state, they can be metabolized and utilized for energy by the body or stored for later use.

  • Carbohydrates, for short-term energy needs
  • Fats for long-term energy needs
  • Proteins supply energy but are often used for building muscle, not providing energy

Some of the energy from the digested food is used to maintain the body's core temperature. Body temperature is tightly regulated by a process known as thermoregulation. Approximately 60 percent of the energy produced is used to maintain body temperature. Even when surrounding temperatures are very different, the body can maintain a consistent core temperature of around 36.5–37.5 °C (or 97.7–99.5 °F).2

The hypothalamus in the brain closely oversees this process, functioning like a thermostat for the body by triggering responses such as sweating or shivering to maintain a steady temperature within a normal range.

Key nutrient deficiencies that affect tiredness and sweating

Inability to regulate body temperature can be linked to various illnesses, medications, or deficiencies in iron, magnesium, potassium, and omega-3 fatty acids.3

Tiredness may also indicate nutritional deficiencies that hinder the body’s energy production. Common deficiencies that lead to fatigue include B vitamins (B2, B3, B5, B6, B9, and B12), vitamin C, vitamin D, iron, and magnesium.1

Iron deficiency (without anaemia)

Iron deficiency without anemia is less commonly diagnosed than iron deficiency anaemia, but it is believed to affect at least double the number of people.4 Iron deficiency can disrupt various metabolic pathways, as iron is essential for transporting oxygen to the body's organs and tissues. A lack of iron can lead to symptoms such as fatigue and tiredness. Furthermore, untreated iron deficiency often progresses to iron deficiency anemia, which can manifest with symptoms including a rapid heart rate, increased anxiety, palpitations, and hot flushes that may lead to excessive sweating.5

The recommended daily iron intake is as follows: 8.7 mg for men aged 19 and older, 14.8 mg for women aged 19 to 49, and 8.7 mg for women aged 50 and older.

Women who continue to have menstrual periods after the age of 50 may require the same amount of iron as those aged 19 to 49.

Getting all the iron you need from your daily diet is possible. Good dietary sources of iron include:

  • Liver 
  • Red meat
  • All types of beans
  • Nuts
  • Dried fruit—such as dried apricots
  • Fortified breakfast cereals
  • Soybean flour

Vitamin D deficiency

Vitamin D is essential for maintaining the health of bones, teeth, and muscles by regulating calcium and phosphate levels. It also supports the immune system by triggering responses to pathogens.6 A deficiency can lead to symptoms like tiredness and fatigue, as well as bone and muscle weakness. While most people can produce sufficient vitamin D from sunlight, this varies by season and location. Limited dietary sources of vitamin D include:

  • Oily fish like salmon, sardines, herring, and mackerel
  • Red meat
  • Liver
  • Egg yolks
  • Fortified products such as breakfast cereals

Additionally, dietary supplements are another option for acquiring vitamin D.

For infants up to 1 year old, a daily intake of 8.5 to 10 micrograms of vitamin D is recommended. Adults should aim for 10 micrograms of vitamin D each day.

Magnesium deficiency

Magnesium deficiency is rare and typically results from prolonged low levels. This mineral supports healthy muscles, nerves, bones, and blood sugar.7 Symptoms include low appetite, nausea, muscle spasms, fatigue, and abnormal heart rhythms. Low magnesium can cause excessive muscle contraction, leading to cramps, as it helps muscles relax by blocking calcium. Adequate magnesium can usually be obtained through a healthy, balanced diet.

A diet plentiful in nuts, seeds and legumes is an excellent way to achieve adequate magnesium intake, such as

  • Pumpkin seeds
  • Chia seeds 
  • Almonds
  • Cashews 
  • Black beans 
  • Peanut butter 
  • Spinach
  • Wholemeal bread

Animal sources of magnesium include:

  • Plain low-fat yogurt 
  • Salmon
  • Chicken breast 
  • 90% lean ground beef

You can find dietary supplements for magnesium. Here are the daily amounts you need:

  • Men (ages 19 to 64): 300 mg
  • Women (ages 19 to 64): 270 mg
  • Children (ages 9 to 13): 240 mg
  • Children (ages 4 to 8): 130 mg

B Vitamins (Especially B12 and Folate)

Vitamins are essential nutrients found in food that support various bodily functions, including energy production and red blood cell formation. Our bodies need 13 vitamins, among which 8 are B-group vitamins. While B-group vitamins don't provide energy directly, they are crucial for utilizing carbohydrates, fats, and proteins for energy and help in DNA creation.

Vitamins B12 and folate are vital for a healthy nervous system, and deficiencies can lead to issues like fatigue and excessive nighttime sweating. Since B vitamins aren’t stored in the body, they must be consumed daily through a balanced diet.

Good sources of vitamin B12 include:

  • Meat
  • Fish
  • Shellfish
  • Fortified breakfast cereals
  • Most dairy products

The daily recommended amount of vitamin B12 varies by age:

  • Babies (0-6 months): 0.4 mcg per day
  • Babies (7-12 months): 0.5 mcg per day
  • Toddlers (1-3 years): 0.9 mcg per day
  • Children (4-8 years): 1.2 mcg per day
  • Children (9-13 years): 1.8 mcg per day
  • Teens (14-18 years): 2.4 mcg per day
  • Adults (19 to 64 years): 1.5 mcg per day

Make sure to meet these daily needs for proper health.

If you eat meat, fish, or dairy, you likely get enough vitamin B12 from your diet. However, vegetarians and vegans may need supplements, as B12 is not present in fruits, vegetables, or grains. 

Folate, also known as vitamin B9, is important for producing healthy red blood cells and reducing the risk of neural tube defects in developing babies. A deficiency in folate can lead to folate deficiency anemia.

Good dietary sources of folate include:

  • Broccoli
  • Brussels sprouts
  • Leafy green vegetables, such as cabbage, kale, spring greens and spinach
  • Peas
  • Chickpeas and kidney beans
  • Liver 
  • Breakfast cereals fortified with folic acid

Daily folate requirements:

  • Adults: 400 micrograms
  • Pregnant Women: At least 600 micrograms
  • Breastfeeding Women: 500 micrograms
  • Adolescents (14–18 years): 400 micrograms
  • Children (9-13 years): 300 micrograms
  • Children (4-8 years): 200 micrograms
  • Children (1-3 years): 150 micrograms

Eat folate-rich foods regularly because the body doesn’t store it. Most people can get enough folate from a balanced diet. If you are trying to get pregnant or are pregnant, take a folic acid supplement daily until 12 weeks of pregnancy.

Electrolyte imbalances (Sodium, Potassium, Calcium)

Cells in the body use electrolytes for electrical signals, which help muscles contract and support important chemical reactions. These processes are vital for hydration and fluid balance inside and outside of cells. Key elements like sodium, potassium, and calcium are essential for maintaining normal electrolyte levels8.

Numerous symptoms can suggest an electrolyte disorder, including 

  • Arrhythmia (a heart rhythm that’s irregular and quicker than usual)
  • Feeling tired and lethargic
  • Nausea
  • Vomiting
  • Feelings of irritation and confusion
  • Headaches
  • Seizures
  • Abnormal bowel habits (constipation or diarrhoea);
  • Abdominal cramps
  • Muscle cramps
  • Muscle weakness
  • Numbness and tingling

Electrolyte disorders happen when there is an imbalance in the body's electrolytes. This imbalance can occur due to losing fluids from the body, like through diarrhea, sweating, or vomiting. It can also happen if a person doesn't drink enough fluids or eat properly. In some cases, a medical issue or certain medications can cause electrolyte problems.

Many common foods are rich in electrolytes, including:

Sodium

  • Dill pickles
  • Clams
  • Table salt
  • Cheese
  • Sunflower seeds

Daily recommended intake of calcium:

  • 800 mg per day for children aged 1 to 3 years
  • 1,000 mg per day for children aged 4 to 8 years
  • 1,200 mg per day for children aged 9 to 13 years
  • 1,500 mg per day for adolescents and adults aged 14 to 70 years

Potassium

  • Bananas
  • Beet greens
  • Salmon
  • White beans
  • Avocado
  • Potatoes
  • Milk
  • Mushrooms

Recommended daily intake of Sodium

  • Adults (19 years and older): 2600-3400 mg per day
  • Teens (14-18 years old): 2300-3000 mg per day
  • Children (9-13 years old): 2300-2500 mg per day
  • Children (4-8 years old): 2300 mg per day
  • Toddlers (1-3 years old): 2000 mg per day

Calcium

  • Milk
  • Cheese
  • Spinach
  • Tofu 
  • Yoghurt
  • Okra
  • Trout

Recommended daily requirements for calcium:

  • Adults: 1000-1300 mg
  • Teens (14-18 years): 1300 mg
  • Children (9-13 years): 1300 mg
  • Children (4-8 years): 1000 mg
  • Toddlers (1-3 years): 700 mg

Zinc deficiency

Zinc plays a vital role in the immune system. It is essential for innate immune cells' normal growth and function, like neutrophils and natural killer (NK) cells.9 Zinc deficiency can also harm macrophages, which are essential for immune response.10

Zinc occurs naturally in foods like

  • Shellfish
  • Meat
  • Poultry
  • Dairy
  • Fortified breakfast cereals and snack bars

Here are the daily zinc requirements for different age groups:

  • Children aged 1 to 3 years need 3 mg
  • Children aged 4 to 8 years need 5 mg
  • Kids aged 9 to 13 years need 8 mg
  • Teens aged 14 to 18 years need between 9 mg and 11 mg
  • Adults aged 19 and older need between 8 mg and 11 mg

How nutritional deficiencies interact with other factors

Stress negatively impacts the body's nutrient reserves, leaving us feeling drained and low on energy. During stressful periods, the body rapidly depletes essential nutrients and struggles to absorb them effectively.

A lack of sleep increases the production of ghrelin, the hormone that triggers hunger, while decreasing leptin, the hormone that signals when we are full11. This imbalance leads to increased hunger and reduced satisfaction after meals, which often results in consuming more calories. Over time, poor sleep combined with unhealthy food choices can contribute to obesity and related health issues.

Additionally, certain health conditions can cause malnutrition. Long-term illnesses may result in symptoms such as loss of appetite, nausea, and changes in bowel habits, including diarrhea and vomiting. Examples of such conditions include cancer, liver disease, and chronic lung diseases like chronic obstructive pulmonary disease (COPD).

Nutrient deficiencies can exacerbate these issues, creating a damaging cycle of poor health.

Summary

Nutrients are essential for good health, and not getting enough of them can cause various health issues.

A nutrient deficiency happens when the body lacks important nutrients, vitamins, and minerals. This can disrupt the balance needed for the body to function well.

It is important to understand how nutrients work and the effects of not having enough to help maintain health and prevent problems in the future. s.

Here are some of the potential effects of nutrient deficiency on the body:

  • Fatigue and tiredness: Vital nutrients are crucial for generating energy, so a lack of them can lead to feelings of fatigue and physical weakness
  • Weakened immune system: Nutrients are essential for a strong immune system, especially if it is already weak. When people lack these nutrients, they are more likely to get infections and illnesses
  • Bone Health Issues: Not getting enough important nutrients like calcium and vitamin D can lead to bone problems, such as osteoporosis. This increases the chance of fractures because the bones become weaker
  • Hormonal Imbalance: Lack of essential nutrients can interfere with regular hormonal processes, possibly resulting in various health problems
  • Increased Risk of Chronic Health Conditions: If nutrient deficiencies continue over an extended period without addressing them, they can raise the risk of chronic health issues such as heart disease, diabetes, and more

References

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Colette Lawler

BSc Oral Health Science, MSc Health Informatics, Dental Hygienist/Therapist & Freelance Medical Writer

Colette Lawler is a healthcare writer with a clinical background in oral health science and a master’s degree in Health Informatics. She specializes in dental and digital health topics, combining hands-on clinical knowledge with expertise in health technology and communication. Her writing focuses on translating complex regulatory, clinical, and educational information into clear, accessible content for healthcare professionals and the public. Passionate about improving health literacy and supporting innovation, she covers areas such as oral health care, digital health advancements, and continuing education for dental professionals.

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