Introduction
What are tonsils?
Tonsils are two small round tissues found at the back of your throat. They are located in the upper airway, and they perform a vital function in the immune system. The tonsils come into contact with a range of foreign antigens here, such as bacteria, viruses, and food particles. Rhinoviruses are an example of this, these are viruses that get in the body through our mouth and nose; mucins, found in the mucus, catch them as they pass through the upper airways and help to fight microbes. Viruses and bacteria can infect the tonsils and cause painful inflammation, called tonsillitis. This article will specifically look at bacterial tonsillitis, typically caused by Streptococcus bacteria.
Understanding tonsillitis
What is tonsillitis?
Tonsillitis is an inflammation of the tonsils caused by an infection. It can be caused by viruses and bacteria like the common cold or Streptococcus pyogenes (Group A strep).
Acute tonsillitis is an inflammation of the tonsillar tissues following an infectious process. Although patients of any age may be impacted, school-aged children are particularly susceptible to acute infections of the palatine tonsils.
The standard course of treatment for viral tonsillitis is supportive care.
Symptoms of tonsillitis
- Sore throat
- Inflamed tonsils, which may be coated in white or yellow patches
- Difficulty swallowing
- Fever
- Bad breath
- Swollen lymph nodes in the neck
Causes of tonsillitis
Tonsillitis is typically caused by viral infections such as the common cold and flu. However, bacterial infections, especially group A strep, can also cause tonsillitis. If left untreated, bacterial tonsillitis can lead to serious complications such as fever, peritonsilar abscesses and kidney inflammation.
The connection between tonsillitis and rheumatic fever
What is rheumatic fever?
Rheumatic fever is an inflammation caused by a streptococcus infection. It occurs when the immune system overreacts to an infection and begins attacking healthy tissue. It can affect the heart, joints, brain and skin and can be fatal if left untreated.
How does tonsillitis cause rheumatic fever?
When bacterial tonsillitis is left untreated, the immune system launches a defensive attack on the body’s tissues. This immune response can cause inflammation in different organ systems such as the joints, heart and blood vessels. Rheumatic fever can lead to rheumatic heart disease, which may cause heart failure or stroke if not treated early.
Symptoms of rheumatic fever
- Fever
- Joint pain and swelling, often in the knees, ankles, elbows, and wrists
- Fatigue
- Chest pain or heart murmur if the heart is affected
- Red, net-like rash on the chest or arms
Tonsillitis and kidney complications
Post-glomerulonephritis (PSGN), a rare form of kidney infection that develops as a result of immune responses to streptococcal infections. It is a delayed immune response that happens due to deposits of immune complexes in the kidneys, which causes inflammation, though kidney function often reverts to normal over time.
Symptoms of kidney complications
- Dark, tea-colored urine (blood in urine)
- Swelling of the face, hands, and feet (oedema)
Diagnosis and management of tonsillitis-related complications
Rheumatic fever
Early treatment with antibiotics can prevent the onset of rheumatic fever. In cases where the condition has already developed, treatment options may focus on managing the symptoms and preventing further complications.
Post-streptococcal glomerulonephritis (PSGN)
PSGN usually resolves on its own, with little long-term impact. However, in rare cases, patients may need treatment for kidney failure or high blood pressure.
Prevention and treatment of tonsillitis
- Good hygiene: Frequent handwashing and avoiding contact with infected individuals can help reduce the risk of tonsillitis
- Seek medical care: Early diagnosis and treatment of tonsillitis, particularly with antibiotics, can prevent complications like rheumatic fever and PSGN
- Complete antibiotic courses: Patients should complete their prescribed antibiotics to ensure the infection is fully treated
- Tonsillectomy: For chronic or recurrent tonsillitis, a doctor may recommend tonsillectomy (surgical removal of the tonsils)
Treatment of tonsillitis
- Bacterial tonsillitis: Antibiotics, typically penicillin, are used to treat bacterial tonsillitis
- Pain management: Pain relief can be provided with medications like paracetamol or ibuprofen
- Rest and hydration: Adequate rest and hydration are crucial for recovery
FAQs
Does tonsillitis cause permanent kidney damage?
In rare cases, untreated tonsillitis can lead to PSGN, which may affect kidney function. However, this condition is usually mild and reversible.
How common is rheumatic fever after tonsillitis?
Rheumatic fever is rare today, thanks to the widespread use of antibiotics. However, it remains a possibility if strep infections are left untreated.
What are the signs of severe tonsillitis?
Signs of severe tonsillitis include high fever, difficulty breathing, pain on swallowing and fever. These symptoms may indicate complications, and immediate medical attention is necessary.
Summary
While tonsillitis is generally considered a minor infection, bacterial tonsillitis, if left untreated, can lead to serious complications such as fever and kidney problems. Early diagnosis and antibiotic treatment are essential to prevent these complications. Tonsillitis can be prevented by good hygiene practices and timely treatment.
References
- Cunningham MW. Pathogenesis of group A streptococcal infections. Clin Microbiol Rev. 2000;13(3):470–511. Available from: https://journals.asm.org/doi/10.1128/cmr.13.3.470
- Steer AC, Batzloff MR, Mulholland K, Carapetis JR. Group A streptococcal vaccines: facts versus fantasy. Curr Opin Infect Dis. 2009;22(6):544–552. Available from: https://journals.lww.com/co-infectiousdiseases/abstract/2009/12000/group_a_streptococcal_vaccines__facts_versus.5.aspx
- Lloyd A, Walker V, Wilks A. Poststreptococcal glomerulonephritis. Pediatrics. 2019;144(2):e20191674. Available from: https://pubmed.ncbi.nlm.nih.gov/30855843

