Introduction
Overview of toenail fungus (onychomycosis)
Onychomycosis is a fungal infection affecting the nail unit. In the case of dermatophytes causing onychomycosis, this condition is called Tinea unguium. The term onychomycosis encompasses mould infections caused by saprophytes, dermatophytes and yeasts. In case of an abnormal nail that is not caused by a fungal infection, it is a dystrophic nail. Onychomycosis can infect both fingernails and toenails, but onychomycosis of the toenail has a higher prevalence.1
Importance of early treatment
The earlier a fungal nail infection is addressed, the easier it is to treat. Catching the infection in its early stages not only reduces the symptom severity but also makes treatment more effective. In the initial phases, treatment options like topical antifungals or oral medications may be sufficient to get rid of the infection. However, if the infection is allowed to progress, more intensive treatments may be necessary.
Benefits of over-the-counter (OTC) treatments
OTC treatments are easily accessible and available. They can effectively treat f mild to moderate cases of nail fungus, providing a convenient and cost-effective way to manage the condition without needing a prescription. These treatments can help prevent the fungus from spreading and assist in restoring the nail’s appearance. Specifically, they are accessible, affordable and convenient..
Common OTC treatments for toenail fungus
Antifungal creams and ointments
These are among the most common OTC treatments. They contain active ingredients like clotrimazole, miconazole or terbinafine, that target the fungal infection directly.
These creams will penetrate the nail and the surrounding skin, thereby killing the fungus and preventing its transmission. Consistent application is key for effectiveness.
Popular Products include:
- Tinactin
- Lotrimin AF
- Lamisil
Antifungal nail polishes
Medicated nail polishes are a novel addition to the OTC antifungal arsenal. These will contain antifungal agents and are applied like regular nail polish.
The polish or varnish will form a barrier over the nail, in turn, allowing the medication to seep in over time. It should typically be used daily and removed weekly to allow for new applications.
Popular products include:
- Amorolfine (Loceryl)
- Ciclopirox (Penlac)
Medicated nail soaks
Nail soaks are infused with antifungal agents that can be an effective way to treat and soothe nails affected due to fungal infection. These soaks often include ingredients like menthol, eucalyptus and tea tree oil.
Soaking the nails softens them and allows the antifungal ingredients to penetrate deeply. It assists in the reduction of inflammation and the relief of any discomfort.
Popular products include:
- Vicks VapoRub
- Dr. G’s Clear Nail Antifungal Treatment
Natural remedies
For those seeking alternative treatments, natural remedies offer a chemical-free approach. Ingredients like tea tree oil, oregano oil, and vinegar are popular for their antifungal properties.
These natural substances have antifungal and antiseptic properties, which can help inhibit fungal growth. However, their effectiveness may vary, and they often require longer treatment durations.
Popular methods
- Tea Tree Oil: Apply directly to the affected nail
- Oregano Oil: Known for its antifungal and antibacterial properties
- Vinegar Soaks: A mixture of vinegar and water can be used to soak the nails
Preventing recurrence
- Keeping your feet clean and dry
- Washing them with soap and water every day
- Drying them off well afterwards
- Avoid going barefoot in public
- Changing your socks and shoes often
- Putting on a clean pair of socks every day
- Giving your shoes a rest and wearing different pairs often
- Using the right footwear
- Keeping tools clean
- Cleaning and sterilising your nail clippers, files, and scissors every time after you use them
- Avoiding nail polish where possible
- Using an antifungal cream
- Never share shoes or socks with others
- Checking your feet and toes regularly this is your chance to catch a fungus in its early stages. If you think you have another infection, like athlete's foot, then talk to your doctor or pharmacist about what needs to be done
Conclusion
Onychomycosis is a fungal infection affecting the nail unit.
Onychomycosis can infect both fingernails and toenails, but onychomycosis of the toenail has a higher occurrence.
The earlier a fungal nail infection is addressed, the easier it is to treat.
OTC treatments are readily accessible as well as available
They can be effective for mild to moderate cases of nail fungus, offering a convenient, cost-effective way for the management of the condition without needing a prescription.
These treatments can prevent the fungus from spreading and assist in restoring the nail’s appearance. Precisely, accessibility, affordability and convenience
References
- Bodman, Myron A., et al. ‘Onychomycosis’. StatPearls, StatPearls Publishing, 2025. PubMed, http://www.ncbi.nlm.nih.gov/books/NBK441853/.
- Contributors WE. OTC and Home Remedies for Toenail Fungus. WebMD. [accessed 28 May 2025] Available from: https://www.webmd.com/skin-problems-and-treatments/otc-home-remedies-foot-fungus
- Toenail Fungus (Onychomycosis/Tinea Unguium): Symptoms & Causes. Cleveland Clinic. [accessed 28 May 2025] Available from: https://my.clevelandclinic.org/health/diseases/11303-toenail-fungus
- Ameen M, Lear JT, Madan V, Mohd Mustapa MF, Richardson M, Hughes JR, et al. British Association of Dermatologists’ guidelines for the management of onychomycosis 2014. Br J Dermatol. 2014;171(5):937–58. [accessed 28 May 2025] Available from: https://academic.oup.com/bjd/article/171/5/937/6616243
- Nail fungus: Learn More – Nail fungus: Polish, cream or tablets? In: InformedHealth.org [Internet]. Institute for Quality and Efficiency in Health Care (IQWiG); 2022. [accessed 28 May 2025] Available from: https://www.ncbi.nlm.nih.gov/books/NBK279546/
- Godwin L. Do Over-the-Counter Toenail Fungus Treatments Work? Dermatology Physicians of Connecticut. 2025. [accessed 28 May 2025] Available from: https://dermatologyofct.com/do-over-the-counter-toenail-fungus-treatments-work/

