Introduction
What is polyhydramnios?
An increase in amniotic fluid during pregnancy is known as polyhydramnios, and it is linked to higher rates of morbidity and death in both mothers and newborns. While the severity of the illness varies, up to one in five of the newborns who are impacted by it are born with a congenital defect.1
It's linked to more foetal death in the womb, early labour, early breaking of the water, prolapsed cord, very big baby, breech birth, c-section, and heavy bleeding after giving birth. These incidents raise the likelihood of both baby and mom getting sick or passing away. Around 20% of the time, polyhydramnios is due to a birth defect. But 60% to 70% of the time, it's not clear why it happens.1
Causes
- Deformities and genetic abnormalities in foetuses
- Gestational diabetes in mothers
- Multiple pregnancies
- Foetal anaemia
- Additional reasons, such as viral infections, Bartter syndrome, neuromuscular diseases, and maternal hypercalcemia
- Polyhydramnios can be caused by viruses such as parvovirus B19, rubella, and CMV infections. Additional illnesses such as syphilis and toxoplasmosis can also result in polyhydramnios3
Symptoms
- Maternal discomfort due to abdominal distension
- Difficulty breathing or eating
- Swelling of lower extremities
- Heartburn or indigestion
- Constipation
Diagnosis of polyhydramnios
Ultrasound tests
Medical practitioners can measure the single largest pocket of amniotic fluid surrounding the infant to screen for polyhydramnios. The maximum vertical pocket is what is known as this (MVP).
Alternatively, they could assess the amniotic fluid index (AFI), which is the fluid in the uterus's four quadrants. When the MVP is 8 or higher or the AFI is 24 or higher, polyhydramnios is detected.2
Classification
Some doctors classify polyhydramnios into three severity classes based on AFI values acquired during prenatal screening:
- Mild polyhydramnios (AFI of 25–30 cm)
- Moderate polyhydramnios (30.1–35 cm)
- Severe polyhydramnios (≥ 35.1 cm)3
Blood tests
- Glucose tolerance test to rule out gestational diabetes in the mother3
- Diagnostic testing for infection3
- Amniocentesis to check for congenital disorders4
- Tests to rule out immunological causes3
- Nonstress test to check for foetal heart rate and overall well being4
Complications of polyhydramnios
- Preterm labour: Excessive amniotic fluid can increase the risk of preterm labour and delivery
- Placental abruption: This is a serious condition where the placenta separates from the uterine wall prematurely, leading to bleeding and potential harm to both mother and baby
- Foetal malpresentation: The excess fluid can make it more difficult for the baby to assume the proper position for delivery, increasing the likelihood of breech or transverse presentation
- Premature Rupture of Membranes (PROM): The amniotic sac may rupture before the full term, increasing the risk of infection and premature birth
- Postpartum haemorrhage: Excessive amniotic fluid can sometimes contribute to increased bleeding after delivery
- Umbilical cord prolapse: There's an increased risk of the umbilical cord slipping down through the cervix ahead of the baby (cord prolapse), which can cause compression and compromise blood flow to the baby
- Respiratory distress syndrome (RDS): In severe cases, the baby may experience breathing difficulties at birth due to underdeveloped lungs, which can occur if the baby is born prematurely
- Stillbirth: Though rare, severe polyhydramnios can be associated with an increased risk of stillbirth
Management of polyhydramnios
When someone's dealing with too much amniotic fluid during pregnancy, it's crucial to keep a close eye on things and take steps to prevent any potential issues. Here are a few ways how it’s handled:
- Regular check-ups: They receive frequent prenatal check-ups to monitor amniotic fluid levels and foetal development through ultrasound scans
- Identifying underlying causes: When doctors are trying to understand why there's too much amniotic fluid, they explore potential reasons like gestational diabetes or carrying more than one baby. Once they figure out what's causing it, they can take steps to address the issue appropriately
- Alleviating discomfort: Measures to alleviate discomfort, such as support belts or recommended exercises, may be suggested
- Amnioreduction (Amniocentesis): In severe cases, therapeutic amniocentesis may be performed to remove excess fluid, reducing the risk of complications like preterm labour
- Treatment of underlying conditions: If polyhydramnios is secondary to a specific medical condition, appropriate management of that condition is crucial
- Monitoring foetal well-being: Continuous monitoring of foetal well-being through tests like non-stress tests or ultrasounds helps ensure the baby's health isn't compromised
- Preparation for delivery: The medical team talks with the pregnant individual about how they want to handle giving birth and any ways they can help make things go smoothly for both them and the baby
Follow-up and prognosis
Following the right treatment and keeping an eye on things, the outlook for people dealing with polyhydramnios can vary.
Factors influencing prognosis
- For mild cases of idiopathic polyhydramnios, the prognosis is very good. The prognosis for both the mother and the foetus gets worse as polyhydramnios increases. Idiopathic polyhydramnios typically resolves on its own and doesn't require medical intervention in most situations1
- The presence of complications during pregnancy or delivery can influence the prognosis. Complications like preterm labour, foetal malpresentation, or umbilical cord issues may require immediate medical intervention and could affect the overall outcome
Keeping watch
- Even after starting treatment, they'll still need regular check-ups to make sure everything's going smoothly. Doctors will keep an eye on the amniotic fluid levels and how the baby is growing to catch any issues early
Potential complications
- Sometimes, despite treatment, there might be complications like early labour or problems with how the baby is positioned. If anything comes up, doctors will step in to handle it
Getting ready for birth
- As they get closer to the due date, doctors will work out a plan for giving birth that keeps both mom and baby safe. This might involve thinking about when and how to deliver the baby depending on how things are going
After the baby arrives
- Once the baby's born, they'll both get checked over to make sure everything's okay. Doctors will keep an eye out for any lingering effects of polyhydramnios or complications from birth
Long-term outlook
- In most cases, with the right care, things turn out fine. But if there were any problems during pregnancy or birth, they might need some extra support down the road. Doctors will be there to help them through it
FAQ’s
What is polyhydramnios?
Polyhydramnios is a condition characterised by an excessive accumulation of amniotic fluid within the amniotic sac during pregnancy.
What causes polyhydramnios?
Polyhydramnios can be caused by various factors, including gestational diabetes, foetal abnormalities, multiple pregnancies (twins, triplets), foetal anaemia, or genetic conditions.
How is polyhydramnios diagnosed?
Polyhydramnios is typically diagnosed through ultrasound examinations that measure the amniotic fluid index (AFI). An AFI greater than 25 cm is considered indicative of polyhydramnios.
What are the symptoms of polyhydramnios?
Polyhydramnios itself may not cause noticeable symptoms in the mother. However, some individuals may experience abdominal discomfort, shortness of breath, or swelling due to the excess fluid.
Are there any risks associated with polyhydramnios?
Polyhydramnios can increase the risk of complications during pregnancy and delivery, including preterm labour, placental abruption, foetal malpresentation, umbilical cord prolapse, and postpartum haemorrhage.
How are polyhydramnios managed?
Polyhydramnios is managed by keeping a close eye on the amniotic fluid levels, figuring out what's causing the issue, helping the mom feel better, sometimes draining off extra fluid, and getting ready for delivery while considering what's best for each situation.
What is the prognosis for polyhydramnios?
The prognosis for polyhydramnios varies depending on factors such as the underlying causes, response to treatment, presence of complications, gestational age, and overall maternal and foetal health. With proper medical care and monitoring, many individuals go on to have successful pregnancies and healthy babies. However, complications can occur and may influence the overall outcome.
Summary
Polyhydramnios, when there's too much amniotic fluid, can be risky for both moms and babies, increasing chances of health problems and even death. It can happen because of things like foetal abnormalities, diabetes during pregnancy, or infections. Doctors use ultrasound and blood tests to diagnose it. Complications include premature labour and breathing problems for babies. To manage it, doctors keep a close watch with regular check-ups, treat underlying issues, and monitor how the baby's doing. Sometimes they need to drain some fluid or manage conditions like diabetes. The outlook varies; some cases clear up on their own, but others can lead to more serious problems. Keeping an eye on things and getting help when needed is key to ensuring the best outcome for both mom and baby.
References
- Hwang DS, Mahdy H. Polyhydramnios. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 [cited 2024 Mar 19]. Available from: http://www.ncbi.nlm.nih.gov/books/NBK562140/
- Polyhydramnios - diagnosis and treatment - mayo clinic [Internet]. [cited 2024 Mar 20]. Available from: https://www.mayoclinic.org/diseases-conditions/polyhydramnios/diagnosis-treatment/drc-20368494
- Hamza A, Herr D, Solomayer EF, Meyberg-Solomayer G. Polyhydramnios: causes, diagnosis and therapy. Geburtshilfe Frauenheilkd [Internet]. 2013 Dec [cited 2024 Mar 20];73(12):1241–6. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964358/
- Cleveland Clinic [Internet]. [cited 2024 Mar 20]. Polyhydramnios: causes, symptoms, complications & treatment. Available from: https://my.clevelandclinic.org/health/diseases/17852-polyhydramnios

