Atrial Fibrillation is a common heart rhythm disorder in which the heart’s upper chamber, called the atria, starts beating in an irregular and chaotic manner. This results in a rapid and inconsistent heart rate, also known as arrhythmia. Unfortunately, atrial fibrillation is quite common for adults, affecting one in every three to five adults over the age of 45.1 Between 2010 and 2019,1 the global rate of atrial fibrillation has increased significantly, as cases of the condition increased from 33.5 million to 59 million.1 Early identification and effective management may decrease the likelihood of complications linked to atrial fibrillation, such as strokes and cardiovascular issues.
Image 1: Depiction of the difference between heart rhythms of a healthy heart vs a heart of a person with atrial fibrillation.
Types of atrial fibrillation
There are five types of atrial fibrillation.2 The frequency of atrial fibrillation and its response to treatment determine the type of atrial fibrillation.
- Paroxysmal atrial fibrillation: the episodes end on their own or after receiving therapy within seven days. However, their frequency of recurrence may be unknown
- Persistent atrial fibrillation: the episodes do not stop on their own and continue regularly for more than seven days.
- Long-term standing atrial fibrillation: the episodes persist consistently for more than a year
- Permanent atrial fibrillation: the episodes are acknowledged, and no more measures are taken to preserve or repair normal sinus rhythm
- Non-valvular atrial fibrillation: episodes occur without the presence of a prosthetic heart valve, mitral valve repair, or rheumatic mitral valve disease
Symptoms
Individuals with atrial fibrillation have a higher risk of stroke and heart failure than those without. Approximately a third of patients do not exhibit symptoms3 and are unaware of their condition. Others may have any of the following symptoms:4
- An irregular heartbeat.
- Heart palpitations (fast, fluttering, or pounding).
- Feeling lightheaded.
- Extreme tiredness.
- Shortness of breath.
- Chest discomfort.
Causes and risks of atrial fibrillation
Atrial fibrillation develops when disruptive electrical impulses in the upper chambers of the heart interfere with its normal rhythm. Usually, the heartbeat begins in the sinoatrial node in the right atrium, leading to coordinated contractions of the atria and ventricles to circulate blood successfully. However, in atrial fibrillation, irregular signals result in the atria contracting irregularly, stopping the upper and lower chambers from working effectively.
There are many ways in which atrial fibrillation can develop. Conditions that alter the heart's tissue or disrupt its electrical signals might cause atrial fibrillation. Atrial fibrillation can also occur as a result of diseases that induce enlargement of the heart muscle tissue.
Other causes of atrial fibrillation:5
- Heart muscle changes
- Cells or mineral buildup in heart tissues and blood vessels
- Reduced blood flow
- Gene mutation
What increases the risk of atrial fibrillation?
Age, family history and genetics, life habits, heart disease or other health issues, race, and medical history all have the possibility of increasing your chances of having the structural and electrical problems and thus, atrial fibrillation. Even in a healthy heart, a rapid or slow heart rate, such as during exercise or sleep, can cause atrial fibrillation. Atrial fibrillation can occur for no clear reason too.6
Other potential risk factors include:
- Diabetes
- Kidney disease
- Obesity
- Hypertension
- Sleep apnea
- Hyperthyroidism
Importance of early detection and monitoring
Atrial fibrillation can evolve from being intermittent (paroxysmal) to persistent or even permanent, making it more difficult to treat and control. As a result, early detection and treatment of atrial fibrillation are critical to preventing it from becoming chronic and potentially leading to serious complications such as cardiac failure, stroke, and death.6
An electrocardiogram (ECG) is one of the most useful tools for detecting atrial fibrillation since it gives a snapshot of the heart's electrical activity in clinical settings and reveals abnormalities such as irregular heartbeat.2
Routine pulse checks, whether performed by a healthcare professional or self-monitored at home via wearable pulse checks like smartwatches, can aid in the early diagnosis of atrial fibrillation. Furthermore, other assessments can be carried if suspicion of atrial fibrillation arises. These assessments include: measuring blood pressure, conducting cardiovascular clinical examinations, undertaking cardiovascular risk assessments and performing thyroid function tests. Early detection of atrial fibrillation allows patients to have a better opportunity of treating the problem with lifestyle modifications, drugs, or treatments before it becomes more challenging to overcome. Likewise, early diagnosis is an essential step in the long-term prevention of persistent atrial fibrillation.12
Lifestyle modifications to prevent progression of atrial fibrillation
Multiple research studies have indicated that healthy lifestyle choices can significantly decrease the frequency, severity, and duration of atrial fibrillation episodes, making lifestyle modification one of the most effective and accessible therapies for preventing the condition from advancing to a persistent form.
Smoking
In one study, present smokers had a risk of atrial fibrillation 2.1 times higher, whereas smokers who changed their lifestyle and stopped smoking had a risk 1.3 times higher. Despite this, in a research study with 15,792 patients, participants who managed to give up smoking only reduced their AF risk by 36%.7
Alcohol
The consumption of alcohol is another risk factor for atrial fibrillation. Researchers reported that for every 0.1% increase in blood alcohol content over the course of 12 hours, there was a 40% increase in the probability of having an episode of atrial fibrillation.8
Hypertension
Hypertension is another recognised cause of atrial fibrillation, with significant research indicating a 56% increase. Atrial fibrillation could be regarded as a component of the hypertension-related end-organ damage spectrum. Consequently, managing hypertension may effectively minimise the chances of having atrial fibrillation.9
Maintaining a healthy weight, quitting smoking, limiting alcohol and caffeine, managing hypertension, and eating a diet that is good for the heart can all help avoid atrial fibrillation progression. Frequent moderate physical activity, reducing stress through meditation, and treatment for sleep apnoea are also important. These improvements improve cardiac function while decreasing atrial fibrillation frequency, degree of severity, and long-term consequences.
Patient education and long-term management
Patients who lack health literacy will struggle to understand atrial fibrillation management and taking care of oneself. Educating patients about atrial fibrillation is critical for effective long-term care and preventing persistent atrial fibrillation development, although this knowledge is frequently restricted. Patients must be effectively informed about treatment alternatives, medication adherence, and the potential consequences of failure to adhere, as well as treatment goals and expectations. Patients should be aware of typical symptoms, including palpitations, exhaustion, and shortness of breath, as well as recognising when to seek medical assistance and report symptoms.10
Some individuals may find that lifestyle changes and drugs are insufficient to treat atrial fibrillation, particularly when symptoms persist or get worse. In such circumstances, interventional techniques such as catheter ablation provide a viable early therapy option.
Interventional procedures for early management
Moreover, some patients may find that lifestyle changes and drugs are insufficient to treat atrial fibrillation, particularly when symptoms persist or worsen. In such circumstances, interventional techniques such as catheter ablation provide a viable early therapy option. Catheter Ablation is a drug-free treatment for a variety of irregular cardiac arrhythmias, with the goal of restoring normal heart rhythm and can improve the quality of life for patients.11
Summary
To prevent the progression of atrial fibrillation, a comprehensive, patient-centred approach is required. Early identification, combined with lifestyle changes, medication and targeted treatment of underlying problems, dramatically minimises the likelihood of AF becoming persistent. Treatments should be customised to each individual to improve long-term heart health and quality of life. Patients and healthcare providers can collaborate to effectively manage atrial fibrillation and avoid long-term consequences by combining education, monitoring, and preventive care.
References
- Linz D, Gawalko M, Betz K, Hendriks JM, Gregory Y.H. Lip, Nicklas Vinter, et al. Atrial fibrillation: epidemiology, screening and digital health. The Lancet Regional Health - Europe [Internet]. 2024 Feb 1;37:100786–6. Available from: https://www.thelancet.com/journals/lanepe/article/PIIS2666-7762(23)00205-3/fulltext.
- Nesheiwat Z, Goyal A, Jagtap M. Atrial fibrillation [Internet]. National Library of Medicine. StatPearls Publishing; 2023. Available from: https://www.ncbi.nlm.nih.gov/books/NBK526072/.
- Atrial Fibrillation Overview: Types, Causes, Symptoms and Treatment | Pfizer [Internet]. www.pfizer.com. Available from: https://www.pfizer.com/disease-and-conditions/atrial-fibrillation.
- Centers for Disease Control and Prevention. About Atrial Fibrillation [Internet]. Heart Disease. 2024. Available from: https://www.cdc.gov/heart-disease/about/atrial-fibrillation.html.
- Chen YH . KCNQ1 Gain-of-Function Mutation in Familial Atrial Fibrillation. Science [Internet]. 2003 Jan 10;299(5604):251–4. Available from: https://science.sciencemag.org/content/299/5604/251.
- National Heart, Lung, and Blood Institute. Atrial Fibrillation - Causes and Risk Factors | NHLBI, NIH [Internet]. www.nhlbi.nih.gov. 2022. Available from: https://www.nhlbi.nih.gov/health/atrial-fibrillation/causes.
- Sabzwari SRA, Garg L, Lakkireddy D, Day J. Ten Lifestyle Modification Approaches to Treat Atrial Fibrillation. Cureus [Internet]. 2018 May 24;10(5). Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6059525/.
- Hatley M, Lam T, Ijeoma Ekeruo, Heinrich Taegtmeyer. Alcohol and Atrial Fibrillation: An Update and New Perspectives. The American Journal of Medicine. 2024 Jul 1.
- James PA, Oparil S, Carter BL, Cushman WC, Dennison-Himmelfarb C, Handler J, et al. 2014 evidence-based guideline for the management of high blood pressure in adults: report from the panel members appointed to the Eighth Joint National Committee (JNC 8). JAMA [Internet]. 2014 Feb 5;311(5):507–20. Available from: https://www.ncbi.nlm.nih.gov/pubmed/24352797/.
- Antoniou P, Dafli E, Giannakoulas G, Igimbayeva G, Visternichan O, Kyselov S, et al. Education of Patients With Atrial Fibrillation and Evaluation of the Efficacy of a Mobile Virtual Patient Environment: Protocol for a Multicenter Pseudorandomized Controlled Trial. JMIR Research Protocols [Internet]. 2024 Jan 23;13(1):e45946. Available from: https://www.researchprotocols.org/2024/1/e45946.
- Ramanathan Parameswaran, Al-Kaisey AM, Kalman JM. Catheter ablation for atrial fibrillation: current indications and evolving technologies. Nature Reviews Cardiology [Internet]. 2020 Oct 13;18:1–16. Available from: https://www.nature.com/articles/s41569-020-00451-x.
- Shaked M, Levkovich I, Adar T, Peri A, Liviatan N. Perspective of healthy asymptomatic patients requesting general blood tests from their physicians: a qualitative study. BMC Family Practice. 2019 Apr 5;20(1).

