Pruritus And Stress
Published on: July 25, 2024
Pruritus And Stress
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Nicole McClean

BSc (Hons) Combined STEM - Health Science, <a href="https://www.open.ac.uk/" rel="nofollow">The Open University</a>

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Richard Stephens

Doctor of Philosophy(PhD), St George's, University of London

Are you experiencing persistent itchiness on your skin that seems to worsen during stressful periods? You’re not alone. Gain useful insights for reducing stress and pruritus and regaining comfort and well-being by comprehending the underlying mechanisms and practical management techniques.

Overview

Pruritus, or persistent itching is a common yet distressing condition.1 Often triggered by various factors, pruritus leads to the irresistible urge to scratch. Simultaneously, stress, the body's reaction to demands or pressure makes pruritus worse through a complicated interaction involving immunological, neuroendocrine, and psychological systems.2.3 Stress activates the hypothalamic-pituitary-adrenal (HPA) axis, which in turn controls the inflammatory pathways associated with pruritus by releasing stress hormones, including cortisol. In addition, stress weakens the skin's barrier function and suppresses immune responses, making people more susceptible to pruritic stimuli.

The relationship between pruritus and stress

Numerous studies have shown that there is a mutual connection between stress and pruritus, with one aggravating the other.6 Research has shown that psychological stress can be brought on by chronic pruritus, creating a vicious cycle of exacerbation, and stress can also cause or worsen pruritus symptoms. Through a variety of physiological and psychological reasons, stress makes pruritus worse. Hormones and neurotransmitters are released during stress, which can intensify itchy feelings. In addition, stress weakens the skin's barrier function and suppresses immune responses, making people more susceptible to triggers that cause pruritus. 

Causes

Pruritus can stem from various sources, including:1

  • Skin conditions. A few instances are dermatitis (dry skin), psoriasis, scabies, burns, scars, insect bites and hives.
  • Underlying medical conditions. Such as kidney disease, liver disease, diabetes, thyroid issues or specific cancers.
  • Neurological conditions. Examples include multiple sclerosis, pinched nerves and shingles.
  • Psychological disorders. Depression, anxiety and obsessive-compulsive disorder.
  • Irritation and allergic reactions. Among other things, wool, chemicals, and soaps can irritate the skin and result in rashes and itching. Materials, like cosmetics or poison ivy, might occasionally trigger an allergic reaction. Itchy skin can also result from drug reactions to certain medications, such as opioid drugs used to alleviate pain.

There are situations where the source of the itching is unknown.

Symptoms

Pruritus manifests primarily as an intense itching sensation on the skin, affecting localised areas such as the scalp, chest or underarms. Or it can cover the whole body.

  • Redness
  • Inflammation
  • Rash
  • Blisters, pimples or bumps
  • Skin that is dry and cracked
  • Scaly or leathery areas

The urge to scratch can become uncontrollable, leading to skin damage, discomfort and further exacerbation of symptoms.

Managing pruritus and stress

Stress reduction techniques

Since stress can intensify itching, pruritus management involves practising stress-reduction strategies. Mindfulness meditation, deep breathing exercises, yoga and progressive muscle relaxation are effective in reducing stress levels and promoting relaxation. Incorporating these techniques into daily routines can help alleviate symptoms.

Lifestyle changes

Adopting a healthy lifestyle can complement medical treatments and stress-reduction techniques in managing pruritus and stress. This includes maintaining a balanced diet, engaging in regular exercise, prioritising adequate sleep and avoiding triggers such as harsh chemicals or allergens that may exacerbate symptoms.

Medications

In addition, several medical treatments and general measures are recommended to alleviate persistent itching, depending on its underlying cause.4

  • Topical corticosteroids. A type of steroid medicine available in four different strengths can be applied directly to the skin to reduce inflammation and irritation. (Advice required from a specialist).5
  • Antihistamines.1 It is not advisable to use topical antihistamines or local anaesthetics as they are either ineffective or very ineffective and can sometimes lead to sensitisation. Alternatively, go for oral antihistamines.
  • Moisturisers. When itching is linked to dry skin or in otherwise healthy older individuals, mild emollients may be helpful. Encourage generous application whenever necessary.
  • Cooling. Simple actions like dressing in light clothing can create a cooler atmosphere. Steer clear of hot water, alcohol, spices, coffee, and other vasodilators, as well as heavy perspiration.

Both symptomatic relief for the itching and the identification and therapy of the underlying cause are goals in the management of pruritus. The main goal of symptomatic treatment is to keep the skin cool and moist.

When to see a doctor?

Pruritus significantly impairs quality of life, affecting daily activities, sleep patterns and emotional well-being.1 Persistent itching can disrupt sleep, leading to fatigue and irritability. Social interactions may be hindered due to embarrassment over visible scratching or skin lesions. In addition, the psychological consequences of persistent pruritus, such as tension, anxiety, and depression may impair quality of life.

Consult your physician or a dermatologist who specialised in skin diseases if symptoms:

  • Persists for longer than two weeks and doesn't get better with self-care
  • Is severe enough to keep you from going about your regular activities or sleep
  • Appears out of nowhere and is difficult to explain
  • Impacts your entire body
  • Includes additional symptoms such as fever, chills, or weight loss.

FAQ’s

Can stress cause pruritus?

Yes, stress can exacerbate pruritus symptoms. According to research, stress causes physiological reactions in the body that might exacerbate pruritus-related skin diseases and increase itchy sensations.

How can I tell if my itching is caused by stress or another condition?

It can be challenging to differentiate between stress-induced itching and itching caused by other factors. Seeking the advice of a medical expert can help identify the root cause of your symptoms by performing a thorough assessment and relevant diagnostic testing.

Can pruritus be completely caused by addressing stress?

While stress management can help lessen the symptoms of pruritus, a comprehensive plan that addresses underlying medical conditions and triggers may be required to fully treat pruritus. Managing stress is just one aspect of effectively managing pruritus it's essential to consult with health professionals for personalised treatment plans.

Can pruritus caused by stress lead to long-term skin damage?

On its own, stress-induced pruritus usually does not result in long-term skin damage, though it can make itching and discomfort worse. However, frequent scratching due to pruritus can potentially cause skin damage, including irritation, redness and the formation of open sores and wounds.

Can stress-related pruritus affect children and adolescents?

Yes, stress-related pruritus can affect individuals of all ages, including children and adolescents. Stress-related itching can be influenced by a variety of factors, including family dynamics, social pressures, and academic pressure. Stressors that might affect children's well-being should be recognised by parents and other carers, and they should seek out the proper assistance and interventions as necessary.

Summary

This article has discussed the common relationship between stress and itching, which can be frustrating for many people. With the right information and useful tactics,  it is possible to break the pattern of discomfort and unease. Both pruritus and stress-related symptoms can be reduced by adopting new lifestyle habits, managing stress using relaxing techniques, and obtaining the necessary medical care. We now know that tension can exacerbate itching and vice versa, but there are strategies to stop the vicious cycle. Remember, you are not alone in this journey. Make time for self-care, seek assistance from medical specialists, and seek support. Our mission is to provide you with easily available information and solutions so you can take back your comfort and well-being. 

References

  1. Tivoli YA, Rubenstein RM. Pruritus. J Clin Aesthet Dermatol [Internet]. 2009 [cited 2024 Jul 15]; 2(7):30–6. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924137/.
  2. Schneiderman N, Ironson G, Siegel SD. STRESS AND HEALTH: Psychological, Behavioral, and Biological Determinants. Annu Rev Clin Psychol [Internet]. 2005 [cited 2024 Jul 15]; 1:607–28. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2568977/.
  3. Sanders KM, Akiyama T. The vicious cycle of itch and anxiety. Neuroscience & Biobehavioral Reviews/Neuroscience and Biobehavioral Reviews [Internet]. 2018 Apr 1;87:17–26. Available from: https://www.sciencedirect.com/science/article/abs/pii/S0149763417305687
  4. NICE Guidance. CKS are only available in the UK [Internet]. NICE. [cited 2024 Apr 9]. Available from: https://cks.nice.org.uk/topics/itch-widespread/
  5. Das A, Panda S. Use of Topical Corticosteroids in Dermatology: An Evidence-based Approach. Indian J Dermatol [Internet]. 2017 [cited 2024 Jul 15]; 62(3):237–50. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448257/.
  6. Sanders KM, Akiyama T. The Vicious Cycle of Itch and Anxiety. Neurosci Biobehav Rev [Internet]. 2018 [cited 2024 Jul 15]; 87:17–26. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845794/.
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Nicole McClean

BSc (Hons) Combined STEM - Health Science, The Open University

Nicole is a freelance healthcare writer with several years of experience in acute mental healthcare. With a Certificate of Higher Education in Psychology and a Diploma in Counselling, Nicole brings a holistic and interdisciplinary approach to healthcare communication and research.

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