Sleep deprivation disrupts the glucose metabolism in your body and may increase the risk of developing Type 2 diabetes. There are hormones in your body which play major roles in regulating sleep cycles and blood sugar levels. During sleep, the body shuts down non-essential functions to conserve energy and resources. Your body secretes the hormones melatonin and cortisol that put you to sleep and save energy. In this article, we will discuss the roles of these hormones and how they link your sleep and blood sugar level.1

Cortisol

Your body releases cortisol under stress. Cortisol stimulates the breakdown of muscle tissue and  promotes the formation of free radicals (elements that can damage cells). Cortisol also has an insulin-like effect on blood sugar level.2

The release of cortisol in blood boosts glucose production in the liver. This increases the release of glucose into the bloodstream, keeping blood sugar levels more stable during sleep.2

The less you sleep, the lesser the release of cortisol, slowing down the glucose metabolism in your body. Frequent lack of sleep may increase your chances of developing type 2 diabetes in the long run.

Melatonin

Your body secretes melatonin at night. As you begin to fall asleep, melatonin production increases, making you calm and relaxed.

Studies suggest there is a strong association between melatonin and insulin. As your body secretes melatonin, the chemicals responsible for insulin secretions become active as well.3

Those with more melatonin have better insulin sensitivity than those with less, allowing more control over the amount of glucose absorbed into their bloodstream from food without causing spikes in insulin levels.3

The Importance of Sleep

Tips for a good night’s sleep

References

  1. Aldabal, L., & Bahammam, A. S. (2011). Metabolic, endocrine, and immune consequences of sleep deprivation. The open respiratory medicine journal, 5, 31–43. doi:10.2174/1874306401105010031
  2. Joseph, J. J., & Golden, S. H. (2017). Cortisol dysregulation: the bidirectional link between stress, depression, and type 2 diabetes mellitus. Annals of the New York Academy of Sciences, 1391(1), 20–34. doi:10.1111/nyas.13217
  3. Garaulet, M., Qian, J., Florez, J. C., Arendt, J., Saxena, R., & Scheer, F. (2020). Melatonin Effects on Glucose Metabolism: Time To Unlock the Controversy. Trends in endocrinology and metabolism: TEM, 31(3), 192–204. doi:10.1016/j.tem.2019.11.011
  4. Knutson, K. L., & Van Cauter, E. (2008). Associations between sleep loss and increased risk of obesity and diabetes. Annals of the New York Academy of Sciences, 1129, 287–304. doi:10.1196/annals.1417.033
  5. Grandner, M. A., Seixas, A., Shetty, S., & Shenoy, S. (2016). Sleep Duration and Diabetes Risk: Population Trends and Potential Mechanisms. Current diabetes reports, 16(11), 106. doi:10.1007/s11892-016-0805-8
  6. Physiology, Obesity Neurohormonal Appetite And Satiety Control [Internet] Treasure Island (FL): StatPearls Publishing. [cited 22 July 2022]. Available at: https://www.ncbi.nlm.nih.gov/books/NBK555906/
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Klarity is a citizen-centric health data management platform that enables citizens to securely access, control and share their own health data. Klarity Health Library aims to provide clear and evidence-based health and wellness related informative articles. 
Email:
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Alum House
5 Alum Chine Road
Westbourne Bournemouth BH4 8DT
VAT Number: 362 5758 74
Company Number: 10696687

Phone Number:

 +44 20 3239 9818
my.klarity.health presents all health information in line with our terms and conditions. It is essential to understand that the medical information available on our platform is not intended to substitute the relationship between a patient and their physician or doctor, as well as any medical guidance they offer. Always consult with a healthcare professional before making any decisions based on the information found on our website.
Klarity is a citizen-centric health data management platform that enables citizens to securely access, control and share their own health data. Klarity Health Library aims to provide clear and evidence-based health and wellness related informative articles. 
Email:
Klarity / Managed Self Ltd
Alum House
5 Alum Chine Road
Westbourne Bournemouth BH4 8DT
VAT Number: 362 5758 74
Company Number: 10696687

Phone Number:

 +44 20 3239 9818
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