The Latest Advancements In Cataract Surgery Technology
Published on: May 9, 2025
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Muhammad Iqbal

Master of Science -MSc, Pharmacology and Drug Discovery, <a href="https://www.coventry.ac.uk/" rel="nofollow">Coventry University, UK</a>

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Yunseo Oh

Drug Development Science MSc, King’s College London

A cataract is the cloudiness of the lens, which is the clear, flexible structure in the eye made up of proteins called crystallins, among others. As they get older, these proteins deteriorate and form cloudy patches, which obscure vision and can be compared to potentially feeling as though one is viewing the world through a foggy window. With time, the condition progresses and impairs daily activities. Cataract formation therefore is usually considered a normal part of the aging process. The most common form of this disease is age-related cataracts. Fortunately, you don't have to put up with deteriorating vision: an ophthalmologist can surgically remove cataracts and let clear sight be restored.1

The only possible removal of cataracts and their restoration to clear vision is through surgery. In this, an ophthalmologist removes the clouded natural lens and replaces it with an intraocular lens (IOL) - a permanent artificial lens. There are various types of IOLs from which you can select, and your provider can help you make that decision. Mainly, the biggest advantage of IOL is clarity, just like your natural lens. It can also fix certain refractive errors and may cut down your dependence on eyeglasses or contacts after surgery.1

Evolution of cataract surgery

Historical overview

Cataract surgery has undergone significant evolution over several centuries - from the early methods of couching, in which the cataract was dislodged but left in the eye, to sophisticated techniques like extracapsular cataract extraction and phacoemulsification. Planned extracapsular cataract extraction (ECCE) is the procedure that removes the lens but keeps the capsule intact and gains popularity over time with its lower complication rates compared to intracapsular cataract extraction, a method involving the removal of the whole lens and capsule. Phacoemulsification, developed during the 1960s, further revolutionised cataract surgical techniques by using ultrasound for fragmenting and aspirating the lens through a small incision, leading to quicker convalescence and fewer complications. Improved visual outcome is also related to the development of intraocular lenses. IOLs not only replace the clouded lens but may also correct refractive errors and reduce the need for using glasses or contacts. The introduction of foldable IOLs and refinements in the methods of calculating the power of IOLs have increased precision such that improved refractive outcomes now result.2

Transition to modern technology

The future of cataract surgery is continuously influenced by technology. Femtosecond laser-assisted cataract surgery can provide incisions and lens fragmentation with more precision than manual phacoemulsification, though it is still a matter of controversy whether femtosecond laser-assisted cataract surgery has advantages over manual phacoemulsification. Intraoperative aberrometry has improved the accuracy of intraocular lens placement in particular. New, adjustable lens technologies, such as light-adjustable and mechanically adjustable IOLs, have postoperative adjustments that will allow fine-tuning of the vision without additional invasive surgery. These newer developments again push cataract surgery to even greater precision, safety, and better visual outcomes, with the goal of near-perfect refractive results for the patient.2

Laser-assisted cataract surgery (femtosecond laser)

Cataract surgery is one of the most performed surgeries worldwide. Phacoemulsification, or PCS, is considered the gold standard technique that allows, to date, excellent outcomes in both visions and refractive correction. Femtosecond laser (FSL) was first used in ophthalmology for corneal surgery. Due to this, the use has expanded to cataract surgery; hence, femtosecond laser-assisted cataract surgery, or FLACS, has been developed. FSLs allow the computer-driven execution of steps such as corneal incisions, capsulotomy, lens fragmentation, and arcuate incisions. These aim at finer, standardised results and reduce the variability introduced by manual surgery. FLACS has various advantages, including high-precision capsulotomies, reduction in required energy for lens fragmentation, and the ability to correct astigmatism during surgery. However, these benefits, including better refractive outcomes and reduced endothelial cell loss, have been inconsistent across studies. Some studies suggest that FLACS has numerous advantages in even the most difficult case scenarios, such as hard cataracts, or diseases like Fuchs' dystrophy.3

Contrary to expectations, despite the technological precision of FLACS, results of clinical trials comparing its superior outcome to PCS are conflicting. The corneal incisions generated by FSL are reproducible but may not be as smooth as the manual ones, leading to questions about postoperative stability. Laser capsulotomies are more precise in size and shape but are made of lower tensile strength and therefore have a higher risk of tears into the anterior capsule. Moreover, intraoperative complications such as miosis and the increased time to perform laser incisions have also been cited. Various studies reported that FLACS seems to reduce ultrasound energy and EPT in some case scenarios; however, significant improvement in endothelial cell loss or visual outcome compared with PCS has not been consistently demonstrated so far. It has also shown some promise in cases involving pediatric cataracts and challenging adult cases, although its wide-ranging benefits over PCS are still under investigation.3

Advanced intraocular lenses (IOLs)

IOLs are clear artificial lenses that are inserted inside the eye either during cataract surgery or refractive lens exchange. They take the place of the eye's natural lens and correct vision problems, such as myopia, hyperopia, presbyopia, and astigmatism. This corrective lens will stay inside the eye permanently and may reduce the dependence on eyeglasses, depending on what type of corrective lens is used. There are many types of intraocular lenses, and they each have advantages. The most common ones are monofocal lenses, which sharpen vision at one distance; multifocal lenses, which improve both near and far vision; EDOF lenses, which provide better range and depth of vision; and accommodative lenses, which adjust themselves to focus at different distances. Toric lenses correct astigmatism, while light-adjustable ones can be fine-tuned after surgery. Phakic lenses preserve the natural lens function in younger patients.4

The type of IOL is determined by specific needs, lifestyle, and priorities concerning vision for a given individual. Some IOLs will require eyeglasses for certain tasks, and some can offer greater independence from eyeglasses but could cause side effects, such as glare. A comprehensive eye examination and discussion with the ophthalmologist are quite necessary in deciding which one will be best. Less common complications from IOL implantation include posterior capsular opacification, a type of secondary cataract; dislocation of the IOL; and uveitis-glaucoma-hyphema syndrome. These, in the main, are treatable, from simple office procedures to further surgery as necessary.4

AI and robotics in cataract surgery

AI in ophthalmology is evolving at an incredible pace, although until recently, the role of AI in cataract surgery has been limited. Currently, AI is being integrated into all parts of the pathway for cataract surgery-from diagnosis to postoperative care. Preoperatively, AI-based image analysis can add value to the detection and grading of cataracts, predict postoperative refraction in children, and optimise intraocular lens power calculations with higher precision when compared with conventional methods. AI-powered tools optimize surgical planning by predictive analytics of lens dislocation, among other complications. During the surgery, AI-enhanced video analysis and situation-aware systems provide real-time decision-making, workflow management, and competence assessment to improve the surgeon's performance and coordination within the operating team. AI-powered video capture, teaching platforms, and robotic systems set new standards in surgical training and efficiency.5

AI optimises postoperative care, particularly the prediction of complications like posterior capsule opacification, thus efficiently triaging those patients and avoiding follow-up visits. Predictive models and AI-managed scheduling further enable better management of operating room usage and reduction of surgical backlog - a finding particularly relevant given the recent unprecedented worldwide demand for cataract surgery. Cataract surgery also continues to transform with the development of smart operating theatres and AI-enhanced robotic systems that make such procedures safer and more efficient. As health care becomes increasingly digital-first, AI is likely to form the backbone of cataract care and improve patient outcomes, while helping to alleviate the growing demand for such surgeries.5

Conclusion

Cataract surgery has amazingly evolved with innovations in laser-assisted techniques, high-precision intraocular lenses, imaging, and AI-robot integration. Femtosecond lasers have refined procedural accuracy, while new intraocular lenses can restore vision to exact needs - even mending refractive errors in the process. AI helps in planning pre-surgically, making decisions during surgery in real-time, and postoperative care for better precision, hence outcomes. All that means, from a patient's point of view, is safety, quick recovery, and substantial improvement in quality of life after surgery.

In this regard, with the advancement of cataract surgery at its epitome, it is of great importance that the patient be updated about the availability of options. An ophthalmologist consultation will help one develop a personal decision so that they can avail of the latest developments that precisely suit their individual vision needs. Such new developments point toward a bright future where individualised solutions and technology improve not only vision but patient overall health.

References

  1. ‘Cataracts: Signs, Symptoms & Treatment’. Cleveland Clinic, Available from: https://my.clevelandclinic.org/health/diseases/8589-cataracts-age-related
  2. Davis, Geetha. ‘The Evolution of Cataract Surgery’. Missouri Medicine, vol. 113, no. 1, Feb. 2016, p. 58. pmc.ncbi.nlm.nih.gov, Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC6139750/
  3. Kecik, Mateusz, and Cedric Schweitzer. ‘Femtosecond Laser-Assisted Cataract Surgery: Update and Perspectives’. Frontiers in Medicine, vol. 10, Mar. 2023, p. 1131314. pmc.ncbi.nlm.nih.gov, Available from: https://doi.org/10.3389/fmed.2023.1131314
  4. ‘IOLs (Intraocular Lens): Pros and Cons’. Cleveland Clinic, Available from: https://my.clevelandclinic.org/health/articles/25099-iols-intraocular-lenses
  5. Lindegger, Daniel Josef, et al. ‘Evolution and Applications of Artificial Intelligence to Cataract Surgery’. Ophthalmology Science, vol. 2, no. 3, Apr. 2022, p. 100164. pmc.ncbi.nlm.nih.gov, Available from: https://doi.org/10.1016/j.xops.2022.100164
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Muhammad Iqbal

Master of Science -MSc, Pharmacology and Drug Discovery, Coventry University, UK

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