Introduction
Every day, you make a conscious effort to eat food and break it down into bite-sized pieces to make it easier to swallow, but what happens after you swallow the food? Do you ever wonder how the food you swallow gets pushed down your body without conscious effort? This is by a process called peristalsis!
What is peristalsis?
Peristalsis is the involuntary muscle movement that performs wave-like motions, contracting and relaxing to push contents along your body.
Mechanism of peristalsis
The biting and chewing of food in the mouth are voluntary responses. In the oesophagus, an involuntary response occurs after swallowing food into the oesophagus:1,2,3
- Peristalsis is stimulated by swallowing as food enters the oesophagus, a tube surrounded by muscles
- Food is propelled along the oesophagus by a series of contractions and relaxation of muscles within the tube, in a wave-like motion
Similar to the oesophagus, the stomach and the small and large intestines are surrounded by muscles that push the food along by peristalsis. Keep reading to understand in detail how peristalsis is involved in the digestive and other systems.
Biology of peristalsis and digestive process
- The parasympathetic nervous system stimulates peristalsis by a network of nerves (e.g. like messengers in your body)
- Our body has a network of nerves that communicate with each other and receive information via signals
- These nerves are stimulated by the stretching of the digestive system or certain chemicals
- This allows the muscle to contract and relax when needed, allowing coordinated movement and the digestive process2
Peristalsis and the digestive system
Peristalsis occurs in different stages of the digestive process:4,5
- In the oesophagus, food is pushed from the oesophagus to the stomach by peristalsis to prepare for digestion
- In the stomach, food is blended and mixed with stomach juices (which helps with digestion and absorption), producing a mixture called chyme. Peristalsis contributes to the mixing and enables the progression of chyme to be slowly transported into the small intestine
- In the small intestine, peristalsis moves chyme slowly along the small intestine into the large intestine while the mixing, digestion and absorption of nutrients from the chyme occurs
- In the large intestine, peristalsis moves chyme along the large intestine while it is further broken down and water is absorbed. Then, peristalsis moves the remaining undigested content and waste products, referred to as faeces, from the large intestine to the rectum
Peristalsis has an essential role in the digestive process and contributes from the start (oesophagus) to the end (rectum) of the digestion process!
Peristalsis and the lymphatic system
One of the many mechanisms lymph uses to circulate throughout the body is “peristalsis within the lymph capillaries.”
Peristalsis and the reproductive system
Another example of the peristalsis process is in the reproductive system. In the female reproductive tract, peristalsis (uterine peristalsis) has been found to have a role:6,7
- during the menstrual cycle
- transporting sperm towards the uterine tube for fertilisation
- in embryo implantation
In the male reproductive system, peristalsis contraction occurs during ejaculation:
- enabling the transportation of spermatozoa (sperm) from the epididymis to the urethra8
Peristalsis and the urinary system
Are you wondering how urine goes from your kidneys to your bladder? Yes, via the ureter by peristalsis! This ensures waste products are removed from your body in a timely manner.
Disorders related to peristalsis
Here are some examples of conditions where peristalsis may be affected by, or peristalsis dysfunction contributes to, the following conditions:2,9,10
- Achalasia is an example of an oesophageal motility disorder characterised by abnormal peristalsis behaviour
- Gastroparesis
- Gastro-oesophageal reflux disease
- Hirschsprung's disease could result in disrupted peristalsis during bowel movement, leading to difficulty in the passing of faeces
- Irritable bowel syndrome (IBS)
- Intestinal pseudo-obstruction
- Small intestinal bacterial overgrowth
Symptoms of impaired peristalsis
The following symptoms of impaired peristalsis can include:2,11
- Dysphagia (problems with swallowing)
- Chest pain
- Constipation
- Diarrhoea
- Heartburn
- Regurgitation
- Vomiting
- Weight loss
Dietary influences
- Some examples of dietary influences include fibre intake and hydration
- Fibre intake can stimulate peristalsis in the intestine, improving bowel movement and defaecation habits and relieving constipation12
Drinking plenty of water and keeping hydrated can soften faeces and prevent constipation.13
To know more about keeping a healthy digestive system, refer to this article: ‘How Can I Heal My Digestive System Naturally?’
Lifestyle factors
- Some examples of lifestyle factors include physical activity and psychological stress
- Physical activity stimulates intestinal peristalsis and prevents constipation13,14,15
- Psychological stress may induce bowel dysfunction and affect bowel habits16
FAQ
What is peristalsis?
A type of involuntary muscle movement that pushes content along the body in a wave-like motion.
What is peristalsis in digestion?
Peristalsis is a type of muscle movement that occurs within your body to move food content along your body for digestion.
Does peristalsis weaken with age?
Yes, there is an association between weakened peristalsis and an increase in age.17
Summary
In summary, peristalsis is an involuntary muscle movement that moves content along your body and is a process that occurs in organ systems such asdigestive, reproductive, urinary and lymphatic. The most common example of peristalsis is in the digestive system, which uses peristalsis from the very start of the digestive process to the end - from the oesophagus to the rectum. This article lists some disorders that affect peristalsis or contribute to the process. Moreover, we list some important dietary influences and lifestyle factors that may stimulate peristalsis or result in bowel habit changes.
References
- Paterson WG. Esophageal peristalsis. GI Motility online [Internet]. 2006 May 16 [cited 2023 Nov 14]; Available from: https://www.nature.com/gimo/contents/pt1/full/gimo13.html
- Patel KS, Thavamani A. Physiology, peristalsis. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 [cited 2023 Nov 14]. Available from: http://www.ncbi.nlm.nih.gov/books/NBK556137/
- Li Y, Kong F. Simulating human gastrointestinal motility in dynamic in vitro models. Comp Rev Food Sci Food Safe [Internet]. 2022 Sep [cited 2023 Nov 14];21(5):3804–33. Available from: https://ift.onlinelibrary.wiley.com/doi/10.1111/1541-4337.13007
- Sensoy I. A review on the food digestion in the digestive tract and the used in vitro models. Current Research in Food Science [Internet]. 2021 Jan 1 [cited 2023 Nov 14];4:308–19. Available from: https://www.sciencedirect.com/science/article/pii/S2665927121000307
- Huizinga JD, Lammers WJEP. Gut peristalsis is governed by a multitude of cooperating mechanisms. American Journal of Physiology-Gastrointestinal and Liver Physiology [Internet]. 2009 Jan [cited 2023 Nov 14];296(1):G1–8. Available from: https://www.physiology.org/doi/10.1152/ajpgi.90380.2008
- Elad D, Jaffa AJ, Grisaru D. Biomechanics of early life in the female reproductive tract. Physiology [Internet]. 2020 Mar 1 [cited 2023 Nov 14];35(2):134-43. Available from: https://www.physiology.org/doi/10.1152/physiol.00028.2019
- Kunz G, Beil D, Huppert P, Leyendecker G. Control and function of uterine peristalsis during the human luteal phase. Reproductive BioMedicine Online [Internet]. 2006 Jan [cited 2023 Nov 14];13(4):528-40. Available from: https://linkinghub.elsevier.com/retrieve/pii/S1472648310606414
- Clement P, Giuliano F. Physiology and pharmacology of ejaculation. Basic Clin Pharma Tox [Internet]. 2016 Oct [cited 2023 Nov 14];119(S3):18–25. Available from: https://onlinelibrary.wiley.com/doi/10.1111/bcpt.12546
- Vaezi MF, Pandolfino JE, Yadlapati RH, Greer KB, Kavitt RT. Acg clinical guidelines: diagnosis and management of achalasia. Am J Gastroenterol [Internet]. 2020 Sep [cited 2023 Nov 14];115(9):1393–411. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9896940/
- Lotfollahzadeh S, Taherian M, Anand S. Hirschsprung disease. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 [cited 2023 Nov 14]. Available from: http://www.ncbi.nlm.nih.gov/books/NBK562142/
- Boeckxstaens GE, Zaninotto G, Richter JE. Achalasia. The Lancet [Internet]. 2014 Jan [cited 2023 Nov 14];383(9911):83–93. Available from: https://linkinghub.elsevier.com/retrieve/pii/S0140673613606510
- Guo K, Yao Z, Yang T. Intestinal microbiota-mediated dietary fiber bioavailability. Frontiers in Nutrition [Internet]. 2022 [cited 2023 Nov 16];9. Available from: https://www.frontiersin.org/articles/10.3389/fnut.2022.1003571
- Diet, fluid and exercise [Internet]. [cited 2023 Nov 16]. Available from: https://www.cancerresearchuk.org/about-cancer/coping/physically/bowel-problems/types/constipation/diet-fluid-exercise
- Kwiatkowska M, Krogulska A. The significance of the gut microbiome in children with functional constipation. Advances in Clinical and Experimental Medicine [Internet]. 2021 [cited 2023 Nov 16];30(4):471–80. Available from: https://www.advances.umed.wroc.pl/en/article/2021/30/4/471/
- Dukas L, Willett WC, Giovannucci EL. Association between physical activity, fiber intake, and other lifestyle variables and constipation in a study of women. The American Journal of Gastroenterology [Internet]. 2003 Aug 1 [cited 2023 Nov 16];98(8):1790–6. Available from: https://www.sciencedirect.com/science/article/pii/S0002927003004428
- Chang YM, El-Zaatari M, Kao JY. Does stress induce bowel dysfunction? Expert Rev Gastroenterol Hepatol [Internet]. 2014 Aug [cited 2023 Nov 16];8(6):583–5. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4249634/
- Bitar K, Greenwood-Van Meerveld B, Saad R, Wiley J. Aging and gastrointestinal neuromuscular function: insights from within and outside the gut. Neurogastroenterol Motil [Internet]. 2011 Jun [cited 2023 Nov 16];23(6):490–501. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3094479/