What Is Pyloroplasty

Pyloroplasty is a surgical procedure that alters the pylorus, a muscular valve located at the bottom of the stomach where it connects to the small intestines. Surgery widens the pylorus, this is done by cutting the pyloric sphincter which controls pylorus activity. The relaxed pyloric sphincter permits faster movement of food into the small intestines.1

Pyloroplasty holds significant importance in medical practice as a surgical intervention designed to address conditions affecting the pylorus, a critical component of the digestive system. By modifying the pyloric sphincter, this procedure aims to alleviate symptoms associated with gastric motility disorders, such as gastroparesis or pyloric stenosis. Pyloroplasty plays a crucial role in improving gastric emptying, thereby enhancing the overall quality of life for individuals suffering from these conditions.2

Indications for pyloroplasty

Some gastrointestinal conditions cause the dysfunction of the pylorus, in the cases where the pylorus has difficulty with gastric emptying, pyloroplasty may be an effective intervention. Peptic ulcers can be treated with a vagotomy, a procedure that damages the nerve supply to the stomach to reduce stomach acid and help reduce the development of peptic ulcers. A vagotomy will also affect pylorus function, therefore the procedure will often be accompanied by a pyloroplasty which will permanently open the pylorus to allow food to pass through. In extreme cases, peptic ulcers can swell or form scar tissue that blocks the opening of the pylorus, in this case, a cut is made to allow access into the small intestines. A pyloroplasty may be needed to reconstruct the pylorus. Gastroparesis is the partial paralysis of the stomach muscles resulting in delayed gastric emptying, doctors may advise a pyloroplasty to open the pylorus.1

Preparation for pyloroplasty

Discussions with your healthcare professional will advise you on the necessary preoperative preparation for the surgery. Patients with symptoms of delayed gastric emptying need a 4-hour solid (or dual) phase nuclear medicine gastric emptying study. All pyloroplasty patients require a preoperative upper endoscopy. Assessments and tests rule out any anatomic abnormalities, for example, gastric outlet obstructions from peptic ulcer disease. Checks must be made for chronic or acute inflammation as it may lead to serious complications.3

The pyloroplasty procedure

The pyloroplasty surgical procedure is designed to address conditions affecting the pylorus. During the operation, the pyloric sphincter is modified to alleviate obstructions or dysfunctions. 

Commonly performed in cases of gastroparesis, peptic ulcers, or pyloric stenosis, pyloroplasty involves a careful incision or dilation of the pyloric sphincter, aiming to improve gastric emptying and alleviate associated symptoms.

Surgical techniques may vary, ranging from open surgery to minimally invasive laparoscopic approaches, providing options tailored to the patient's condition and medical history. It is crucial for individuals considering pyloroplasty to consult with their healthcare providers to determine the most appropriate approach based on their specific diagnosis and overall health.

General anaesthesia and antibiotics are administered before the operation. For an isolated pyloroplasty, extensive monitoring may not be necessary, however when a more complex operation (combined surgeries) is needed, extensive monitoring is required.3 Pyloroplasty is often combined with Nissen fundoplication or esophagectomy. For combined surgery, the patient must be positioned with their arms tucked and legs abducted. For isolated pyloroplasty, the surgeon may stand on the left side of the patient, working in a triangulated manner.

The surgery begins with the surgeon making an incision in the abdominal wall, exposing the stomach and pyloric region. The next step involves careful identification and isolation of the pyloric sphincter, a muscular valve controlling the passage of food from the stomach into the small intestine. Depending on the specific condition, the surgeon may choose to make an incision in the pyloric sphincter (known as a Heineke-Mikulicz pyloroplasty) or perform a longitudinal incision and then close it transversely (Finney pyloroplasty). 

Alternatively, minimally invasive laparoscopic techniques may be employed, involving smaller incisions and the use of specialised instruments. Following the modification of the pyloric sphincter, the surgeon ensures proper closure of the incisions to maintain the integrity of the digestive tract. Postoperatively, patients are monitored for recovery, and appropriate measures are taken to manage pain and ensure a smooth healing process.4

Recovery and post-operative care

In the postoperative phase of pyloroplasty, patients undergo a critical period of recovery, necessitating vigilant monitoring, and comprehensive care. Immediate post-surgery patients are closely monitored for vital signs and potential complications, such as bleeding or infection. Pain management strategies are employed, with the administration of analgesics to ensure patient comfort. Dietary changes play a pivotal role in the recovery process, as individuals may initially follow a modified diet to facilitate healing and ease the transition for the modified pyloric region. This typically involves a gradual reintroduction of solid foods as tolerated by the patient. Nutritional guidance is paramount, with a focus on maintaining adequate nutrient intake to support healing and prevent malnutrition. 

Despite the overall safety of pyloroplasty, potential complications may arise, including infection, bleeding, or adverse reactions to anaesthesia. Early detection and prompt intervention are crucial in managing these complications effectively. Patients are educated on warning signs and advised to seek immediate medical attention if they experience any concerning symptoms during the recovery period.5

Expected outcomes

Pyloroplasty is associated with promising outcomes, often leading to a substantial relief of symptoms and an enhanced quality of life for patients grappling with conditions such as gastroparesis or pyloric stenosis. By addressing the underlying issues related to impaired gastric emptying, this surgical intervention aims to alleviate symptoms such as nausea, vomiting, and abdominal pain. The long-term impact of pyloroplasty is frequently positive, allowing patients to resume a more regular diet and enjoy improved overall well-being.

Follow-up care is integral to ensuring sustained success, typically involving regular check-ups with healthcare providers to monitor recovery progress and address any emerging issues. Patient testimonials and success stories often underscore the transformative effects of pyloroplasty, providing insights into the tangible improvements experienced by individuals post-surgery. While individual experiences may vary, the overall consensus in the medical literature supports the effectiveness of pyloroplasty in bringing about enduring symptom relief and a positive impact on patients' lives.6

Risks and complications

Pyloroplasty, while generally considered a safe and effective surgical procedure, is not without risks and potential complications. Common surgical risks include infection, bleeding, and adverse reactions to anaesthesia, as with any abdominal surgery. Long-term considerations involve the possibility of scarring at the surgical site, which could lead to the recurrence of symptoms or the need for further interventions. Additionally, there may be a risk of delayed gastric emptying, although this is typically rare and can often be managed with appropriate medical attention. 

Potential side effects may include changes in bowel habits or the development of gastroesophageal reflux. It is essential for both healthcare providers and patients to engage in thorough preoperative discussions to assess individual risk factors and address concerns. While the overall safety profile of pyloroplasty is well-established, a comprehensive understanding of potential risks and complications is crucial for informed decision-making and optimal postoperative care. 5

Alternatives to pyloroplasty

In cases where pyloroplasty may not be the preferred or viable option, alternative approaches exist for addressing conditions such as peptic ulcers and gastroparesis. Non-surgical options for peptic ulcers often include pharmacological treatments, such as proton pump inhibitors (PPIs) or H2 receptor blockers, to reduce gastric acid production and promote ulcer healing. For gastroparesis, dietary modifications, medications like prokinetic agents, and gastric electrical stimulation are among the non-surgical interventions aimed at improving gastric motility. 

Alternatively, other surgical procedures may be considered. For peptic ulcers, procedures like vagotomy or antrectomy may be performed, while gastroparesis might be managed with gastric bypass surgery or implantation of a gastric neurostimulator. The choice between pyloroplasty and these alternatives depends on the specific diagnosis, severity of symptoms, and individual patient factors, highlighting the importance of a comprehensive evaluation and discussion between healthcare providers and patients.7


To summarize, pyloroplasty emerges as a pivotal surgical intervention with significant implications for the treatment of digestive disorders. The procedure, targeting the pylorus and its associated dysfunctions, holds promise in alleviating symptoms and improving the quality of life for individuals grappling with conditions like gastroparesis or pyloric stenosis. The prospective benefits extend beyond immediate symptom relief, encompassing enhanced digestive function and increased tolerance to regular dietary intake.

However, it is essential for patients to recognize the individualised nature of medical care, emphasising the importance of consulting with a medical professional for personalised advice. Every patient's condition is unique, and considerations such as medical history, overall health, and specific diagnoses play a crucial role in determining the most suitable treatment approach. Pyloroplasty stands as a testament to the advancements in surgical techniques addressing digestive disorders, underscoring the need for a collaborative and informed decision-making process between patients and healthcare providers to ensure the most effective and tailored care.


  • Pyloroplasty [Internet]. Available from: https://my.clevelandclinic.org/health/treatments/23388-pyloroplasty
  • Parkman HP, Hasler WL, Fisher RS, American Gastroenterological Association. American Gastroenterological Association technical review on the diagnosis and treatment of gastroparesis. Gastroenterology. 2004 Nov;127(5):1592–622.
  • Hunter JG, Spight DH, Sandone C, Fairman JE. Pyloroplasty. In: Atlas of Minimally Invasive Surgical Operations [Internet]. New York, NY: McGraw-Hill Education; 2018 [cited 2023 Nov 11]. Available from: accesssurgery.mhmedical.com/content.aspx?aid=1162530413
  • Horgan S, Kelly KA, Operative Techniques in General Surgery. 2005, 7(2), 101-105
  • Brunicardi FC, Andersen DK, Billiar TR, Dunn DL, Kao LS, Hunter JG, et al. Schwartz’s Principles of Surgery. In: Schwartz’s Principles of Surgery, 11e [Internet]. New York, NY: McGraw-Hill Education; 2019 [cited 2023 Nov 11]. Available from: accessmedicine.mhmedical.com/content.aspx?aid=1175835034
  • Tang DM, Friedenberg FK. Gastroparesis: approach, diagnostic evaluation, and management. Dis Mon. 2011 Feb;57(2):74–101.
  • Søreide K, Thorsen K, Harrison EM, Bingener J, Møller MH, Ohene-Yeboah M, et al. Perforated peptic ulcer. Lancet. 2015 Sep 26;386(10000):1288–98.
This content is purely informational and isn’t medical guidance. It shouldn’t replace professional medical counsel. Always consult your physician regarding treatment risks and benefits. See our editorial standards for more details.

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Ngoc Mai Nguyen

Pharmacology BSc, University College London

Mai is a recent graduate with years of experience with academic writing. With a special interest in human disorders, she has experience assisting the publication of scientific journals on autism and Fragile X Syndrome.

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