What Is Spinal Fusion?
Published on: August 25, 2025
What Is Spinal Fusion?
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Malak Mohammed Saed Abdulqadir

Bachelor of Medicine, Bachelor of Surgery - MBBS, Medicine, <a href="https://limu.edu.ly/" rel="nofollow">Libya International Medical University</a>

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Sungbeen Lee

BSc Neuroscience and Physiology, University of Toronto

Introduction

The backbone is held upright by an interconnecting column made up of ring-shaped bones that strengthen the structure of the body, which is called the Spine. A spinal fusion is a surgical procedure used to fuse two or more vertebrae together in the spine.

When you need to do it 

Here are a few examples of conditions for which this operation is necessary:

Congenital spine diseases (scoliosis, kyphosis or kyphoscoliosis, etc.)  

Pediatric scoliosis is associated with signs and symptoms such as decreased lung function, increased pain, and decreased quality of life; all of which worsen in adulthood. even if the curve remains stable. In 1941, the American Orthopaedic Association reported that 70% of patients treated surgically had a good or poor outcome. The deformity remained unchanged or worsened. Despite early intervention, lung function and deformity outcomes are worse in patients treated surgically before the age of 10 years.  

Spinal stenosis  

Spinal stenosis is characterised by spinal canal narrowing. This is a common and debilitating cause of back and leg pain in older adults, affecting an estimated 103 million people worldwide. Most cases are treated conservatively. Each year, only about 600,000 surgeries for lumbar spinal stenosis are performed in the United States.

Degenerative spondylolisthesis  

Degenerative Spondylolisthesis is a displacement of a vertebra above the underlying vertebrae with degenerative changes without associated impairment or defect of the vertebral annulus. Conservative management includes physical therapy, epidural steroid injections and pain medication. However, if the problem cannot be resolved, surgical options may include decompression alone or decompression and fusion.

Degenerative disc disease 

Degenerative Disc Diseases are degenerative processes of intervertebral discs. It most often affects the nucleus pulposus of the intervertebral disc and eventually the biomechanics of the whole spine. There are many factors that can affect disc integrity, such as mechanical, traumatic, genetic, and nutritional factors

Tumours 

A mass that impacts the bones, soft tissues, and nerve tissue in and around your spine.

Why you should do it

Among other things, a spinal fusion may relieve numbness, discomfort, and muscular weakness. Your spinal cord and the spinal nerves that extend from it may be compressed if there is weakness in any part of your spine. Increasing pressure on your spinal cord or nerves can cause problems with the impulses that pass through them, leading to pain and difficulties performing specific movements.

Here are a few examples of conditions for which this operation is necessary: Tumours that impact the bones, soft tissues, nerve tissue in and around your spine or congenital spine diseases.    

Different techniques

Transforaminal lumbar interbody fusion (TLIF) is utilised for stabilisation and treatment of degenerative lumbar illness after failed preservationist treatment. Comparative prove based on interbody fusion technique, anterior lumbar interbody fusion ( ALIF) vs. transforaminal lumbar interbody fusion (TLIF). Carefully chosen patients with degenerative disc illness and spinal deformities are amenable to surgical intervention with anterior lumbar interbody fusion (ALIF) or transforaminal lumbar interbody fusion (TLIF). While both approaches include removal of the degenerative plate and insertion of an interbody device, the front and back approaches are both related with their claim of one-of-a-kind benefits and challenges. Reported significantly higher disc height, segmental lordosis and total lumbar lordosis within the ALIF group compared with transforaminal lumbar interbody fusion (TLIF). Posterior lumbar interbody fusion (PLIF) vs. transforaminal lumbar interbody fusion (TLIF) are both commonly utilised back approaches for fusion surgery, and speak to the majority of cases performed around the world in terms of LIF. To begin with, as described in 1940 by Cloward, posterior lumbar interbody fusion (PLIF) permits three-column fixation with 360° fusion and front support. 

How surgery is done 

 Preoperative phase

  1. Make the diagnosis first confirmed by imaging (X-ray, CT scan or MRI)
  2. The doctor ensures that you are fit for surgery by running some physical examination, laboratory tests and an echocardiogram
  3. The surgeon decides which technique is suitable for your condition
  4. Finally, you receive written consent

Intraoperative phase

  1. Patient received general anaesthesia with endotracheal intubation and mechanical ventilation
  2. Lidocaine bolus and infusion started after the patient was placed.
  3. Surgical approach (anterior, posterior, or lateral)
  4. Removal of damaged disc or bone
  5. Placement of bone graft or bone substitute
  6. Use of hardware (rods, screws, cages)
  7. Fusion technique (interbody fusion, posterolateral fusion, etc.)
  8. Wound closure

Postoperative phase

  1. Extubated before being transferred to the post-anaesthesia care unit for observation
  2. Giving an  IV hydromorphone, patient-controlled pain relief, and paracetamol
  3. Intravenous and oral antiemetics were administered as needed
  4. Received deep venous thromboembolism prophylaxis using a pneumatic compression device
  5. He/She had at least one physical therapy session on the day of surgery, and he had two physical therapy sessions a day until he was able to move independently and safely climb stairs
  6. Follow-up care and appointments

Recovery

  1. Initial recovery period
  2. Physical therapy and exercises
  3. Restrictions on activities
  4. Long-term outlook and expected results

The risks of surgery

The most common major non-life-related complication is nonunion, with 9 surgeries requiring reoperation, followed by 8 nerve root injuries, and 8 superficial infections. Of his eight surgeries that resulted in severe nerve root injury, three surgeries resulted in persistent neurological deficits. Minor complications occurred in 58.3%.

The most common minor complications were transient confusion and delirium. 6 surgeries resulted in mild nerve root injury, resulting in temporary and non-permanent neurological deficits.

Other complications

  • Coagulopathy
  • Decreased number of dead platelets
  • Sepsis
  • Severe pulmonary embolism
  • Vascular damage during or after a cerebrovascular attack
  • Changes in pain on the electrocardiogram
  • Changes in the tracheal
  • Colitis infection
  • Deep meningitis

Summary

Increasing pressure on your spinal cord or nerves can cause problems with the impulses that pass through them, leading to pain and difficulties performing specific movements. There are different surgical techniques which would help relieve and manage your symptoms that may interfere with your daily life.

References

  1. Professional CC medical. Spinal Fusion: A valuable treatment option [Internet]. [cited 2024 Apr 11]. Available from: https://my.clevelandclinic.org/health/treatments/25168-spinal-fusion
  2. Mobbs RJ, Phan K, Malham G, Seex K, Rao PJ. Lumbar interbody fusion: Techniques, indications and comparison of interbody fusion options including PLIF, TLIF, Mi-TLIF, OLIF/ATP, LLIF and alif [Internet]. U.S. National Library of Medicine; 2015 [cited 2024 Apr 11]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039869/
  3. Fujita, Takuya, et al. “COMPLICATIONS OF SPINAL FUSION IN ADULT PATIENTS MORE THAN 60 YEARS OF AGE.” Orthopedic Clinics of North America, vol. 29, no. 4, Oct. 1998, pp. 669–78. DOI.org (Crossref), https://doi.org/10.1016/S0030-5898(05)70040-7.
  4. Launay, O., et al. Instrumented PLIF in Lumbar Degenerative Spine: Principles, Indications, Technical Aspects, Results, Complications and Pitfalls. Jan. 2016, https://doi.org/DOI:10.1007/978-3-662-47756-4_31.
  5. Hawes, Martha. “Impact of Spine Surgery on Signs and Symptoms of Spinal Deformity.” Pediatric Rehabilitation, vol. 9, no. 4, Jan. 2006, pp. 318–39. DOI.org (Crossref), https://doi.org/10.1080/13638490500402264.
  6. Soffin, Ellen M., et al. “Enhanced Recovery after Lumbar Spine Fusion.” Anesthesiology, vol. 133, no. 2, Aug. 2020, pp. 350–63. DOI.org (Crossref), https://doi.org/10.1097/ALN.0000000000003346.
  7. Katz, Jeffrey N., et al. “Diagnosis and Management of Lumbar Spinal Stenosis: A Review.” JAMA, vol. 327, no. 17, May 2022, pp. 1688–99. PubMed, https://doi.org/10.1001/jama.2022.5921
  8. Bydon, Mohamad, et al. “Degenerative Lumbar Spondylolisthesis: Definition, Natural History, Conservative Management, and Surgical Treatment.” Neurosurgery Clinics of North America, vol. 30, no. 3, July 2019, pp. 299–304. PubMed, https://doi.org/10.1016/j.nec.2019.02.003.
  9. Kos, Natasa, et al. “A Brief Review of the Degenerative Intervertebral Disc Disease.” Medical Archives (Sarajevo, Bosnia and Herzegovina), vol. 73, no. 6, Dec. 2019, pp. 421–24. PubMed, https://doi.org/10.5455/medarh.2019.73.421-424.
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Malak Mohammed Saed Abdulqadir

Bachelor of Medicine, Bachelor of Surgery - MBBS, Medicine, Libya International Medical University

Malak Abdulqadir (Alagoury) , a dedicated medical professional, embarked on her journey in the field of healthcare with a profound commitment to making a difference. Born and raised in Libya, she pursued her undergraduate education at the Libyan International Medical University in Benghazi, where she earned her Bachelor of Medicine and Bachelor of Surgery (MBChB) degree. Demonstrated a keen interest in cardiac medicine, eventually securing a position as a Senior House Officer (SHO) at the prestigious Benghazi Cardiac Center. Beyond her clinical duties, she is passionate about medical research and writing. She actively engages in exploring new developments in cardiology and contributing to the advancement of medical knowledge through her research endeavors.

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