Introduction
Pertussis, commonly known as whooping cough, remains a significant public health challenge despite the availability of effective vaccines. Vaccination coverage for pertussis varies widely across different regions and populations, reflecting disparities in healthcare access, public awareness, and policy implementation. By understanding the facts and figures surrounding pertussis vaccination, one can better appreciate the importance of maintaining high immunisation levels.1
Vaccination coverage for pertussis
As of recent data, the vaccination coverage for pertussis varies significantly by region and age group. In many developed countries, such as the United States, coverage rates for the DTaP (Diphtheria, Tetanus, and Pertussis) vaccine in children are relatively high, often exceeding 90% for the primary series by age 2. However, the Tdap booster vaccine, recommended for adolescents and adults, has lower coverage rates, typically ranging between 60-80%.2
Factors influencing vaccination coverage
Vaccination coverage for pertussis is influenced by a complex interplay of factors that include public awareness and education, healthcare access, government policies and programs, and sociocultural factors. Understanding these factors is crucial for identifying barriers and implementing effective strategies to improve vaccination rates.
Public awareness and education
Public awareness and education play pivotal roles in influencing vaccination coverage. Effective public health campaigns can significantly boost vaccination rates by informing the public about the dangers of pertussis and the benefits of vaccination. Conversely, misinformation and vaccine hesitancy can severely undermine these efforts. Vaccine hesitancy often stems from unfounded fears and myths about vaccine safety, which can spread rapidly through social media and other platforms. Educational initiatives that provide accurate information, address common concerns, and highlight the safety and efficacy of vaccines are essential to counteract misinformation and encourage vaccination.3
For example, studies have shown that parents who receive clear, evidence-based information about the risks of pertussis and the benefits of vaccination are more likely to vaccinate their children. Public health organisations must invest in robust communication strategies, including the use of social media, community outreach, and partnerships with trusted healthcare providers to disseminate accurate information and build public trust in vaccines.
Healthcare access
Access to healthcare services is another critical factor affecting vaccination coverage. In many regions, particularly in rural and low-income areas, access to healthcare can be limited due to geographic, economic, and infrastructural barriers. These barriers include a lack of nearby healthcare facilities, transportation challenges, and financial constraints that prevent individuals from seeking preventive care, including vaccinations.3
To improve vaccination coverage, it is essential to enhance healthcare access by expanding the availability of vaccination clinics, offering mobile vaccination units, and providing financial assistance or subsidies for low-income families. Additionally, integrating vaccination services into routine healthcare visits and offering vaccines at convenient locations such as schools, pharmacies, and community centres can help ensure that more people receive timely vaccinations.
Government policies and programs
Government policies and programs play a significant role in determining vaccination coverage. Countries with strong national immunisation programs and policies, such as mandatory school-entry vaccination requirements, generally report higher vaccination rates. These policies help ensure that children receive essential vaccines before entering school, thereby reducing the risk of outbreaks in educational settings and the broader community.
For instance, the United States and many European countries have implemented school vaccination requirements, which have been effective in maintaining high coverage rates for childhood vaccines. Additionally, government-funded immunisation programs that provide free or low-cost vaccines to the public can help reduce financial barriers and increase vaccination uptake.4
However, the effectiveness of these policies depends on consistent implementation and enforcement. Governments must ensure that vaccination requirements are upheld and that exemptions are limited to genuine medical reasons. Moreover, continuous monitoring and evaluation of immunisation programs are necessary to identify gaps and areas for improvement.
Sociocultural factors
Sociocultural factors, including cultural beliefs, practices, and social norms, can significantly influence vaccination acceptance and coverage. In some communities, cultural beliefs about health and medicine may lead to resistance to vaccination. For example, certain religious groups may have concerns about vaccine ingredients or perceive vaccination as unnecessary due to their beliefs in natural immunity or alternative medicine.5
To address these sociocultural barriers, it is crucial to engage with community leaders, religious authorities, and local influencers who can advocate for vaccination within their communities. Tailoring public health messages to align with cultural values and addressing specific concerns in a respectful and culturally sensitive manner can help increase vaccine acceptance.
Furthermore, community-based interventions, such as vaccination drives organised by local organisations and peer education programs, can effectively promote vaccination in culturally diverse communities. By involving community members in the planning and implementation of these initiatives, public health agencies can build trust and foster a sense of ownership and responsibility towards vaccination.
The importance of pertussis vaccination
Pertussis is a highly contagious respiratory disease that can be severe, especially in infants and young children. Vaccination is the most effective way to prevent pertussis and its complications. The DTaP vaccine, administered in multiple doses starting from infancy, and the Tdap booster, recommended for adolescents and adults, provide robust protection against the disease.2
Current vaccination coverage data
Here are some key statistics on pertussis vaccination coverage:
- United states: According to the Centres for Disease Control and Prevention (CDC), about 95% of children aged 19-35 months received at least three doses of DTaP by 2021. However, Tdap coverage among adolescents aged 13-17 was around 88% in the same year
- Europe: The European Centre for Disease Prevention and Control (ECDC) reports that DTaP vaccination coverage is generally high across Europe, with most countries achieving over 90% coverage for the primary series by age 2. Tdap booster coverage varies but is generally lower, similar to the U.S. rates
- Global perspective: The World Health Organization (WHO) highlights significant regional disparities in pertussis vaccination coverage. High-income countries typically report high coverage, while low- and middle-income countries struggle with lower rates due to limited healthcare infrastructure and access issues2
Challenges in achieving high vaccination coverage
Several challenges hinder the achievement of optimal pertussis vaccination coverage:
- Vaccine hesitancy: Misinformation and distrust in vaccines can lead to lower vaccination rates. Public health initiatives must address these concerns through transparent communication and education
- Healthcare inequities: Disparities in healthcare access, particularly in underserved and rural areas, result in lower vaccination coverage. Efforts to improve healthcare infrastructure and accessibility are crucial6
- Logistical barriers: Maintaining the cold chain for vaccine storage and distribution, especially in remote areas, is a significant challenge. Enhancing logistical support can help mitigate this issue
- Policy implementation: Inconsistent implementation of vaccination policies and lack of enforcement can lead to gaps in coverage. Strengthening policy frameworks and ensuring compliance is essential
Efforts to improve vaccination coverage
Several initiatives aim to improve pertussis vaccination coverage:
- Enhanced public health campaigns: Governments and health organisations are investing in comprehensive public health campaigns to raise awareness about the importance of pertussis vaccination7
- Strengthening immunisation programs: Improving national immunisation programs and ensuring they are well-funded and effectively managed can boost vaccination rates
- Improving access to vaccines: Expanding healthcare services to underserved areas and reducing financial barriers to vaccination can enhance coverage
- Monitoring and surveillance: Implementing robust monitoring and surveillance systems helps identify coverage gaps and target interventions effectively
FAQs
What is pertussis?
Pertussis, or whooping cough, is a highly contagious respiratory disease caused by the bacterium Bordetella pertussis. It is characterised by severe coughing fits and can be particularly dangerous for infants and young children.9
What vaccines are available for pertussis?
The DTaP vaccine (diphtheria, tetanus, and acellular pertussis) is given to children in a series of doses starting from infancy. The Tdap booster (tetanus, diphtheria, and acellular pertussis) is recommended for adolescents and adults.
Why is pertussis vaccination important?
Vaccination is the most effective way to prevent pertussis and its complications. High vaccination coverage helps protect vulnerable populations, such as infants who are too young to be fully vaccinated.10
What are the common side effects of pertussis vaccines?
Common side effects include redness and swelling at the injection site, mild fever, and irritability. Severe side effects are rare.
How can vaccination coverage be improved?
Improving public awareness, ensuring easy access to vaccines, strengthening immunisation programs, and addressing vaccine hesitancy are key strategies to improve vaccination coverage.3
Summary
In summary, pertussis vaccination coverage varies widely across different regions and age groups. While many high-income countries achieve high coverage rates for the DTaP vaccine in children, the Tdap booster coverage remains lower. Factors such as public awareness, healthcare access, government policies, and sociocultural influences significantly impact vaccination rates. Addressing challenges like vaccine hesitancy, healthcare inequities, and logistical barriers is crucial to improving coverage. Ongoing efforts, including public health campaigns and strengthened immunisation programs, are essential to enhancing pertussis vaccination coverage globally.8
References
- Homaira N, He WQ, McRae J, Macartney K, Liu B. Coverage and predictors of influenza and pertussis vaccination during pregnancy: a whole of population-based study. Vaccine. 2023 Oct 13;41(43):6522–9.
- Immunization coverage [Internet]. [cited 2024 May 17]. Available from: https://www.who.int/news-room/fact-sheets/detail/immunization-coverage
- van Zoonen K, Ruijs WLM, De Melker HE, Bongers MEJ, Mollema L. How to increase awareness of additional vaccinations; the case of maternal pertussis vaccination. BMC Public Health [Internet]. 2021 Jun 29 [cited 2024 May 17];21(1):1257. Available from: https://doi.org/10.1186/s12889-021-11344-0
- GOV.UK [Internet]. [cited 2024 May 17]. Supporting immunisation programmes. Available from: https://www.gov.uk/government/publications/health-protection-in-schools-and-other-childcare-facilities/supporting-immunisation-programmes
- de Munter AC, Ruijs WLM, Ruiter RAC, van Nimwegen DJJ, Oerlemans AJM, van Ginkel R, et al. Decision-making on maternal pertussis vaccination among women in a vaccine-hesitant religious group: Stages and needs. PLoS ONE [Internet]. 2020 Nov 12 [cited 2024 May 17];15(11):e0242261. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660565/
- Ekezie W, Awwad S, Krauchenberg A, Karara N, Dembiński Ł, Grossman Z, et al. Access to Vaccination among Disadvantaged, Isolated and Difficult-to-Reach Communities in the WHO European Region: A Systematic Review. Vaccines [Internet]. 2022 Jun 28 [cited 2024 May 17];10(7):1038. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9324407/
- MacDougall DM, Halperin SA. Improving rates of maternal immunization: Challenges and opportunities. Hum Vaccines Immunother [Internet]. 2015 Nov 9 [cited 2024 May 17];12(4):857–65. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962946/
- Suryadevara M, Domachowske JB. Prevention of pertussis through adult vaccination. Hum Vaccines Immunother [Internet]. 2015 Jul 3 [cited 2024 May 17];11(7):1744–7. Available from: https://doi.org/10.1080/21645515.2015.1038442
- del Valle-Mendoza J, del Valle-Vargas C, Aquino-Ortega R, del Valle LJ, Cieza-Mora E, Silva-Caso W, et al. Clinical characteristics and molecular detection of Bordetella pertussis in hospitalized children with a clinical diagnosis of whooping cough in Peru. Iran J Microbiol [Internet]. 2021 Feb [cited 2024 May 17];13(1):23–30. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8043828/
- Marchal C, Belhassen M, Guiso N, Jacoud F, Van Ganse E, Le Pannerer M, et al. Vaccination coverage rates for Diphtheria, Tetanus, Poliomyelitis and Pertussis booster vaccination in France between 2013 and 2017: Learnings from an analysis of National Health System Real-World Data. Vaccine. 2021 Jan 15;39(3):505–11.

