Oranges Benefits For Liver Health

  • Nick Gibbins BSc (Hons) Biochemistry, University of Sussex

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Oranges, a variety of nutritious citrus fruits, bring health benefits to those who incorporate them into a balanced and diverse diet. Oranges can bolster skin health, maintain a lean calorie count, and potentially reduce the likelihood of various health issues. Oranges support liver health through antioxidants, detoxification, and anti-inflammatory properties, while their fibre content aids digestion and weight management. This article lists some benefits of oranges that can promote liver health.

Importance of liver health

The liver, a vital organ within the human body, plays a multifaceted role that encompasses filtering harmful toxins from the bloodstream, processing and metabolising fats, carbohydrates, and proteins, maintaining balanced levels of sugar and cholesterol, and contributing to the digestive process. Consequently, it is imperative to make dietary choices that promote the overall well-being and proper functioning of this vital organ.

Nutritional composition of oranges

Oranges are a popular and nutritious fruit known for their high vitamin C content, but they also contain a variety of other vitamins, minerals, and phytochemicals that contribute to their health benefits. 

Vitamins in oranges:

  1. Vitamin C: Oranges are a good source of vitamin C (ascorbic acid). Vitamin C is crucial for supporting the immune system, maintaining healthy skin, and promoting the healing of wounds.
  2. Vitamin A: Oranges contain small amounts of vitamin A, primarily in the form of beta-carotene, which is a precursor to vitamin A. Beta-carotene is important for vision and overall skin and mucous membrane health.

Minerals in oranges:

  1. Potassium: Oranges contain potassium, an electrolyte that helps regulate blood pressure and maintain proper muscle and nerve function.
  2. Calcium: Oranges contain small amounts of calcium, which is important for bone health and muscle function.
  3. Thiamine (Vitamin B1) and Riboflavin (Vitamin B2): Oranges contain small amounts of these B vitamins, which are important for energy metabolism.

Phytochemicals in oranges:

  1. Flavonoids: Oranges are rich in flavonoids, including hesperidin and naringenin. These compounds have antioxidant properties and are associated with various health benefits, including reduced inflammation and improved heart health. 
  2. Carotenoids: In addition to beta-carotene, oranges contain other carotenoids like lutein and zeaxanthin, which are important for eye health and may help protect against age-related macular degeneration.
  3. Citrus Limonoids: These phytochemicals found in citrus fruits, including oranges, have been studied for their potential anti-cancer properties.
  4. Pectin: Oranges are a good source of dietary fibre, including soluble fibre called pectin. Pectin can help regulate digestion, lower cholesterol levels, and stabilise blood sugar levels.

Antioxidant properties of oranges

Oranges are a rich source of various antioxidants, with vitamin C being one of the most prominent. Antioxidants play a crucial role in supporting liver health. Here are some key aspects of the role of antioxidants in liver health:

Neutralising free radicals

Antioxidants, like vitamins C and E, can donate electrons to unstable free radicals, stabilising them and preventing them from causing oxidative damage to liver cells.1 Oranges are well known for their rich content of vitamin C, which is a powerful water-soluble antioxidant that helps protect cells from oxidative damage. It also supports the immune system, aids in collagen production, and improves the absorption of non-heme iron from plant-based foods.

Anti-Inflammatory properties 

Chronic inflammation is a common factor in liver diseases like hepatitis and non-alcoholic fatty liver disease (NAFLD). Citrus fruits, like oranges, contain antioxidants known as flavonoids, including hesperidin, naringin, and naringenin. These compounds have antioxidant properties and may have various health benefits, including anti-inflammatory and anti-cancer effects. Studies suggest that these compounds may play a role in slowing down the progression of hepatic fibrosis. Hepatic fibrosis is a harmful condition characterised by the excessive buildup of connective tissue in the liver, often stemming from chronic inflammation.2

Detoxification support

The liver serves as the body’s primary organ for detoxification. Antioxidants aid in the detoxification process by supporting liver enzymes and pathways responsible for metabolising and eliminating toxins. Citrus fruits, such as oranges, limes, and lemons, are known to enhance the liver's natural detoxification capabilities. Even when consumed in modest quantities, these fruits stimulate the liver to produce essential enzymes for eliminating toxins from the body.3

Fibre and digestive health

Citrus fruits are a good source of fibre, and they offer several health benefits as a result. Some of these include improving digestive health by promoting regular bowel movements and preventing constipation. Additionally, it can aid in weight loss by increasing feelings of fullness, which may lead to reduced calorie intake. Research evidence suggests that foods high in fibre can help promote weight management.4

How does fibre benefit the liver?

Digestive health and liver health are closely linked. The liver produces bile for fat digestion, detoxifies toxins, and metabolises nutrients. It regulates blood sugar, stores vitamins/minerals, and aids the immune system. Digestive disorders can harm liver health. One cup of orange segments contains approximately four grams of fibre. This is a notable amount of fibre, and it contributes to your daily fibre intake. Research evidence indicates that foods high in fibre can ensure that the liver is functioning properly.5 

Incorporating oranges into your diet

Ways to incorporate oranges into your diet:

  1. Fresh orange slices as a snack.
  2. Freshly squeezed orange juice (in moderation).
  3. Blend oranges into smoothies.
  4. Add orange segments to salads.
  5. Use orange zest in recipes.
  6. Create orange-based marinades.
  7. Make orange salsa for meats or fish.

Recipes and meal ideas featuring oranges:

  1. Orange Glazed Chicken:
    • Ingredients: Orange juice, chicken breasts, soy sauce, honey, garlic, orange zest and ginger. 
    • Recipe: Sear the chicken, then simmer in a sauce made from the other ingredients until cooked through and glazed.
  2. Citrus Salad
    • Ingredients: Orange segments, feta cheese, grapefruit segments, sliced almonds, mixed greens, and a citrus vinaigrette dressing.
    • Recipe: Toss all ingredients together and drizzle with the vinaigrette for a refreshing salad.
  3. Orange-Ginger Salmon:
    • Ingredients: Orange juice, salmon filets, grated ginger, soy sauce, garlic and honey.
    • Recipe:  Marinate salmon in a mixture of orange juice, ginger, garlic, soy sauce, and honey, then bake or grill until flaky.
  4. Orange Smoothie:
    • Ingredients: Oranges, Greek yoghurt, honey, and ice.
    • Recipe:  Blend peeled and segmented oranges with yoghurt, honey, and ice for a creamy and healthy smoothie.

Potential risks

Potential allergies or sensitivities to oranges:

  1. Some individuals might experience allergies or sensitivities to oranges, leading to symptoms such as swelling, hives, itching, and problems related to digestion.
  2. If you think that you may have an allergy or sensitivity to oranges, consult an allergist for testing and guidance.

Moderate consumption:

  1. While oranges are a healthy fruit, moderation is key, especially for those monitoring sugar intake.
  2. Orange juice can be high in natural sugars, so consider limiting the quantity or diluting it with water.

Interaction with certain medications:

  1. Oranges, particularly grapefruit, can interact with certain medications by affecting how they are metabolized in the body.
  2. If you are on medication, consult with your healthcare provider to ensure oranges won't interfere with your treatment.

Summary

Oranges offer a range of health benefits, particularly in promoting liver health. They are rich in antioxidants, including vitamin C, which helps neutralize free radicals and support liver cell protection. Oranges also contain anti-inflammatory flavonoids that may help combat liver diseases. Additionally, the fibre content in oranges aids in digestion and weight management, which is crucial for overall liver function. 

To incorporate oranges into your diet, you can enjoy them fresh, as juice (in moderation), in smoothies, salads, and various recipes. However, be cautious of potential allergies, medication interactions, and sugar content in orange juice, emphasizing moderation for those monitoring their sugar intake.

References 

  1. Lv X, Zhao S, Ning Z, Zeng H, Shu Y, Tao O, et al. Citrus fruits as a treasure trove of active natural metabolites that potentially provide benefits for human health. Chemistry Central Journal [Internet]. 2015 Dec [cited 2023 Sep 28];9(1):68. Available from: https://bmcchem.biomedcentral.com/articles/10.1186/s13065-015-0145-92.
  2. Chen L, Xia S, Wang S, Zhou Y, Wang F, Li Z, et al. Naringenin is a potential immunomodulator for inhibiting liver fibrosis by inhibiting the cgas-sting pathway. J Clin Transl Hepatol [Internet]. 2023 Feb 28 [cited 2023 Sep 28];11(1):26–37. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9647116/
  3. Fishertitus.org. [cited 2023 Sep 28]. Available from: https://www.fishertitus.org/healthy-living/healthy-living-blog/2018/what-foods-cleanse-your liver/#:~:text=Citrus%20Fruits%3A%20Fruits%20like%20grapefruit,enzymes%20that%20flush%20out%20pollutants.
  4. Akbar A, Shreenath AP. High fiber diet. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 [cited 2023 Sep 28]. Available from: http://www.ncbi.nlm.nih.gov/books/NBK559033/
  5. Liver disease diets: fatty liver diet and more [Internet]. 2022 [cited 2023 Sep 28]. Available from: https://liverfoundation.org/health-and-wellness/healthy-lifestyle/liver-disease-diets/

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MSc, Health Psychology, University of Surrey, UK
BSc, Psychology, University of Surrey, UK

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