What Is A Latex Allergy?

Latex allergy is a condition where the immune system reacts to proteins found in natural rubber latex. If you're looking for information about latex allergy, I can provide you with a clear understanding of what it is and how it can be managed.

Latex allergy is an immune system response to proteins found in natural rubber latex. When individuals with latex allergy come in contact with latex products, their immune system recognizes these proteins as harmful and triggers an allergic reaction. Symptoms can range from mild skin irritation to severe respiratory issues and even life-threatening anaphylaxis. It is important to minimize exposure to latex and work with healthcare professionals for accurate diagnosis and appropriate management.


Latex allergy is an immune system response to proteins found in natural rubber latex. It can cause a range of allergic reactions, from mild skin irritations to severe and potentially life-threatening anaphylaxis.

There are two main types of latex allergy: Type I (immediate hypersensitivity) and Type IV (delayed hypersensitivity). Type I latex allergy is most common, and it involves the release of immunoglobulin E (IgE) antibodies upon exposure to latex, causing symptoms like itching, hives, sneezing, and respiratory issues. Type IV latex allergy, also known as contact dermatitis, typically manifests as a delayed skin reaction characterized by redness, rash, and itching.

Risk factors for latex allergy include repeated exposure to latex products, such as in the setting of certain occupations or healthcare, as well as a history of allergies or atopic conditions. 

Latex-fruit syndrome is an additional concern, where individuals with latex allergy may also experience allergic reactions to certain fruits due to cross-reactivity.

The diagnosis of latex allergy involves a combination of medical history assessment, physical examination, and allergy testing, such as skin prick tests and blood tests for latex-specific IgE antibodies.

The primary approach to managing latex allergy is to avoid latex exposure. This includes identifying latex-containing products and using latex-free alternatives whenever possible. Medications like antihistamines and epinephrine auto-injectors may be prescribed to alleviate symptoms or address severe reactions. Allergen immunotherapy (allergy shots) may also be considered in certain cases.

If you suspect latex allergy or experience symptoms after latex exposure, it is important to consult with a healthcare professional, preferably an allergist or immunologist, for proper diagnosis, guidance on avoidance strategies, and appropriate treatment options.1

Types of latex allergy

Type 1

Type 1 latex allergy is the most common form of latex allergy. It is an IgE-mediated allergy, meaning that immunoglobulin E is involved in the immune response to latex exposure.  Symptoms occur within minutes and include itching, hives sneezing, runny nose, watery eyes, wheezing, and difficulty breathing. and can lead to anaphylaxis, a serious condition that needs medical attention.1

Type IV 

Is where there is delayed hypersensitivity or contact dermatitis; this occurs 24 to 48 hours after contact with latex. This is where the immune system responds to chemicals related during the manufacturing process, not the latex itself. Symptoms include redness, rash, and itching. Swelling and blistering of skin.1 

Latex fruit syndrome 

Is where those with a latex allergy have cross-reactivity to certain fruits and vegetables, this is where proteins found in latex resemble proteins in certain fruits like bananas, avocados, kiwis, chestnuts, and papayas. Therefore, those with a latex allergy react to these fruits and develop symptoms of swelling of lips, mouth or throat, hives, abdominal pain, and anaphylaxis.1

Causes of latex allergy

Various factors associated with latex may cause an allergic response. Latex proteins derived from sap of rubber tree (hevea brasiliensis), contain allergenic proteins, usually Hev b 1, that trigger a reaction as the immune system recognises the origin and causes the reaction. 

Occupational exposure 

Some occupations that cause frequent and prolonged exposure to latex products have a higher risk of latex allergy. Some examples of this are nurses, doctors, and dental professionals who use gloves, masks and other medical devices that contain latex.  This can develop after repeated exposure over time. Originally, there were no symptoms over time and exposure, and then exposure caused a reaction. Gain sensitization developed the allergy.


Those with latex allergy can also experience cross-reactivity to certain foods. These foods may contain the allogeneic proteins mentioned earlier. Can be found in fruits like bananas and kiwis. 

It's worth noting that latex allergy is relatively uncommon, and not everyone who is exposed to latex will develop an allergy. However, for those who are sensitized or have a known latex allergy, it is important to take precautions to avoid further exposure and manage symptoms appropriately.

Signs and symptoms of latex allergy

The severity of allergy will vary from person to person.

  • Pruritus
  • A rash can develop on areas of the skin that came into direct contact with latex products. 
  • Hives 
  • Reactions can affect the respiratory systems and cause sneezing, a runny or stuffy nose, and nasal congestion
  • Anaphylaxis

Signs of anaphylaxis include difficulty breathing, rapid heartbeat, severe drop in blood pressure, dizziness, loss of consciousness, and swelling of the face, throat, or tongue. Anaphylaxis requires immediate medical attention

Allergic reactions can also affect the eyes, causing them to be affected by allergic conjunctivitis, where eyes become red, itchy and excessively tearing of the eyes. Ear irritation can lead to them being itchy, and inflammation of the ear canal can cause discomfort.

The gastrointestinal tract can also be affected, causing nausea and vomiting.

Management and treatment for latex allergy

Management and treatment of latex allergy involves avoiding latex exposure and the use of medications to control symptoms. 

Identification of what triggers an allergic reaction is key; this would allow for avoiding the use of latex-containing products and substituting them for latex-free alternatives. By informing your healthcare providers, like dentists, they can make arrangements and take the appropriate precautions to prevent you from developing a reaction.

Medications that can be used to minimize symptoms can be found over the counter.  Antihistamines can alleviate mild symptoms such as watering eyes and sneezing.

Nasal corticosteroid sprays can be used to reduce inflammation and relieve nasal congestion and sneezing. Eye drops can relieve itchy, watery eyes caused by allergic conjunctivitis.

If there are severe reactions that lead to anaphylaxis, a patient may be prescribed an epinephrine auto-injector (epi-pen); this will enable more time for a patient to reach medical attention at a hospital.  Allergy shots are a form of allergen immunotherapy and can be used to reduce allergy symptoms. This is done through exposure to controlled amounts of latex allergens over time.


A health provider will conduct a thorough evaluation of a patient's medical history, looking at any symptoms experienced from latex exposure, when they start and finish and any risk factors in their lifetime.

If present, physical symptoms can be assessed. At the same time, a skin prick test can be performed. Where a small amount of the allergen is placed on the skin, the skin is pricked and then left for 15-20 minutes. Any symptoms observed can help diagnose allergies.

Blood tests for latex-specific IgE antibodies can be performed. They can measure the levels of these antibodies, which are produced in response to latex proteins and allergies.

Patch testing can be used for those who displace symptoms of contact dermatitis or delayed response to latex. Patches with small amounts of latex are applied and then left for 48-72 hours, with symptoms checked afterwards. 

Those with allergies to latex fruit are given food and then monitored under medical supervision.


How can I prevent latex allergy?

  • To prevent latex allergy, it is important to minimize exposure to latex products. Here are some preventive measures:
  • Identify latex-containing products and choose latex-free alternatives.
  • Inform healthcare providers, employers, and others about your latex allergy.
  • Avoid environments where latex is prevalent, such as medical facilities or certain workplaces.
  • Consider wearing a medical alert bracelet or carrying an allergy card to inform others about your latex allergy.

How common is latex allergy?

Latex allergy is relatively uncommon but can affect individuals who have regular exposure to latex products. The prevalence varies depending on the population studied, but it is estimated that about 1-6% of the general population may be sensitized to latex, with a smaller percentage experiencing clinically significant allergic reactions.

Who is at risk of latex allergy?

There are several factors that can increase the risk of developing latex allergy:

  • Healthcare workers and individuals with frequent or prolonged exposure to latex products, such as rubber industry workers.
  • Individuals with a history of other allergies or allergic conditions may have an increased risk of developing latex allergy.
  • Individuals who have undergone multiple surgeries or medical procedures requiring the use of latex-containing products.

What can I expect if I have a latex allergy?

If you have a latex allergy, you can expect allergic reactions upon exposure to latex products. The symptoms can vary from mild to severe and may include itching, skin redness or rash, hives, nasal congestion, sneezing, coughing, wheezing, difficulty breathing, and in severe cases, anaphylaxis. Latex-fruit syndrome may also manifest with symptoms such as oral itching, swelling, and abdominal discomfort after consuming certain fruits.

When should I see a doctor?

  • It is advisable to consult with a doctor if you suspect you have a latex allergy or experience symptoms after latex exposure. You should see a doctor if you have:
  • Repeated allergic reactions after contact with latex.
  • Symptoms that significantly affect your quality of life or daily activities.
  • Symptoms of anaphylaxis, such as difficulty breathing, severe swelling, or loss of consciousness, require immediate medical attention.
  • Uncertainty or concern about your symptoms and need for proper diagnosis and management.


Latex allergy is an immune system reaction to proteins found in natural rubber latex. It can cause a range of symptoms, including skin reactions, respiratory symptoms, eye and ear irritation, gastrointestinal issues, and in severe cases, anaphylaxis. Latex allergy can be diagnosed through medical history assessment, physical examination, and specific allergy tests like skin prick tests and blood tests.

Prevention of latex allergy involves minimizing exposure to latex products and opting for latex-free alternatives. Management includes avoiding latex, using medications to control symptoms, and carrying an epinephrine auto-injector for emergencies. The prevalence of latex allergy is relatively low, but certain individuals, such as healthcare workers and those with a history of allergies, may be at higher risk. If you suspect latex allergy or experience symptoms after latex exposure, it is recommended to consult with a healthcare professional for accurate diagnosis and appropriate treatment.


  1. Pollart SM, Warniment C, Mori T. Latex allergy. afp [Internet]. 2009 Dec 15 [cited 2023 Nov 9];80(12):1413–8. Available from: https://www.aafp.org/pubs/afp/issues/2009/1215/p1413.html
This content is purely informational and isn’t medical guidance. It shouldn’t replace professional medical counsel. Always consult your physician regarding treatment risks and benefits. See our editorial standards for more details.

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